Skip Navigation

This Article
Right arrow Full Text (PDF )
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (21)
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Zaidi, J.
Right arrow Articles by Tan, S.L.
Right arrow Search for Related Content
PubMed
Right arrow Articles by Zaidi, J.
Right arrow Articles by Tan, S.L.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Human Reproduction, Vol. 10, No. 1, pp. 44-49, 1995
© 1995 European Society of Human Reproduction and Embryology

Luteinized unruptured follicle: morphology, endocrine function and blood flow changes during the menstrual cycle

J. Zaidi1, D. Jurkovic, S. Campbell, W. Collins, A. McGregor2 and S.L. Tan

Departments of Obstetrics and Gynaecology, King's College School of Medicine and Dentistry Denmark Hill, London SE5 8RX, UK 2 Medicine, King's College School of Medicine and Dentistry Denmark Hill, London SE5 8RX, UK

Correspondence: 1To whom correspondence should be addressed

A case of spontaneous luteinized unruptured follicle syndrome is presented with full documentation of hormonal, morphological and haemodynamic changes. Changes in uterine blood flow were also noted. Growth of the leading follicle was slow during the follicular phase of the cycle. After the luteinizing hormone (LH) surge, growth of the follicle was more rapid. Concurrently, the follicle developed internal echogenicity with ultrasonic evidence of separation of the granulosa cell layer. The follicle was no longer visible 144 and 132 h after the LH rise and peak respectively. There was no primary progesterone rise associated with either the LH rise or peak, but a secondary progesterone rise occurred 42 h after the onset of the LH surge. Peri-follicular blood flow velocity was detected for the first time on cycle day 5 and appeared to rise after the onset of the LH surge. Peri-follicular blood flow velocity appeared to reduce after the LH surge to values associated with the follicular phase. These observations are consistent with an association of a primary granulosa cell defect with luteinized unruptured follicle syndrome which would account for the initial slow follicular growth, absent primary progesterone rise and reduction in blood flow in the wall of the follicle after the LH surge.

Key words: follicle/luteinized/peri-ovulatory/ultrasonography

Submitted on May 20, 1994; accepted on August 16, 1994.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Hum ReprodHome page
H. Qublan, Z. Amarin, M. Nawasreh, F. Diab, S. Malkawi, N. Al-Ahmad, and M. Balawneh
Luteinized unruptured follicle syndrome: incidence and recurrence rate in infertile women with unexplained infertility undergoing intrauterine insemination
Hum. Reprod., August 1, 2006; 21(8): 2110 - 2113.
[Abstract] [Full Text] [PDF]

Home page
 Hum ReprodHome page
P. Pellizzari, C. Esposito, F. Siliotti, S. Marchiori, and M. Gangemi
Colour Doppler analysis of ovarian and uterine arteries in women with hypoestrogenic amenorrhoea
Hum. Reprod., December 1, 2002; 17(12): 3208 - 3212.
[Abstract] [Full Text] [PDF]

Home page
 Hum ReprodHome page
M. Pall, B. E. Friden, and M. Brannstrom
Induction of delayed follicular rupture in the human by the selective COX-2 inhibitor rofecoxib: a randomized double-blind study
Hum. Reprod., July 1, 2001; 16(7): 1323 - 1328.
[Abstract] [Full Text] [PDF]

Home page
 Biol. Reprod.Home page
B. D. Murphy
Models of Luteinization
Biol Reprod, July 1, 2000; 63(1): 2 - 11.
[Abstract] [Full Text]

Home page
 Journal of Diagnostic Medical SonographyHome page
S. F. Bork
Female Reproductive Arterial Blood Flow and Its Relation to Infertility
Journal of Diagnostic Medical Sonography, November 1, 1996; 12(6): 281 - 286.
[Abstract] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.