Skip Navigation

This Article
Right arrow Full Text (PDF )
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (44)
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Macleod, I.C.
Right arrow Articles by Irvine, D.S.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Macleod, I.C.
Right arrow Articles by Irvine, D.S.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Human Reproduction, Vol. 10, No. 3, pp. 580-586, 1995
© 1995 European Society of Human Reproduction and Embryology

research-article

Andrology: The predictive value of computer-assisted semen analysis in the context of a donor insemination programme

I.C. Macleod and D.S. Irvine1

Department of Obstetrics and Gynaecology, University of Aberdeen, Aberdeen Maternity Hospital Foresterhill, Aberdeen AB9 2ZD, UK

Correspondence: 1To whom correspondence should be addressed at: MRC Reproductive Biology Unit, Centre for Reproductive Biology, 37 Chalmers Street, Edinburgh EH3 9EW, UK

In this paper we examine the value of both conventional and computer-assisted semen analysis (CASA) using the Hamilton-Thorn HTM-S 2030 in predicting the in-vivo fertility of cryopreserved donor semen. Semen samples were examined prospectively and data on the conventional criteria of semen quality, sperm morphometry and movement were collected. Of 61 ejaculates identified, 33 achieved pregnancies (‘successful’) and 28 failed to do so (‘unsuccessful’), despite insemination into at least four different normal female recipients. When the post-thaw semen profiles were compared, no differences were observed between the two groups in respect of the conventional criteria of semen quality determined by conventional laboratory techniques; however, there were differences in respect of both morphometry and movement characteristics determined by the HTM-S. When multiple logistic regression was used to examine the ability of the variables measured to predict the achievement of pregnancy, the conventional criteria of semen quality were of no value (X2 = 6.67, P = 0.353). However, the CASA assessment successfully predicted outcome in 86.9% of cases (X2 = 44.3, P = 0.0021). It was concluded that CASA assessment is of significant value in predicting the ability of an ejaculate to achieve pregnancy.

Key words: computer-assisted semen analysis/donor insemination/Hamilton-Thorn/male infertility/semen analysis


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 J AndrolHome page
A. A. Y. Khalil, A. M. Petrunkina, E. Sahin, D. Waberski, and E. Topfer-Petersen
Enhanced Binding of Sperm With Superior Volume Regulation to Oviductal Epithelium
J Androl, November 1, 2006; 27(6): 754 - 765.
[Abstract] [Full Text] [PDF]

Home page
 J AndrolHome page
C.-H. Chen, S.-S. Lee, D.-C. Chen, H.-H. Chien, I-C. Chen, Y.-N. Chu, J.-Y. Liu, W.-H. Chen, and G.-J. Wu
Apoptosis and Kinematics of Ejaculated Spermatozoa in Patients With Varicocele
J Androl, May 1, 2004; 25(3): 348 - 353.
[Abstract] [Full Text] [PDF]

Home page
 J AndrolHome page
S. M. Duty, A. M. Calafat, M. J. Silva, J. W. Brock, L. Ryan, Z. Chen, J. Overstreet, and R. Hauser
The Relationship Between Environmental Exposure to Phthalates and Computer-Aided Sperm Analysis Motion Parameters
J Androl, March 1, 2004; 25(2): 293 - 302.
[Abstract] [Full Text] [PDF]

Home page
 J AndrolHome page
A. Agarwal, R. K. Sharma, and D. R. Nelson
New Semen Quality Scores Developed by Principal Component Analysis of Semen Characteristics
J Androl, May 1, 2003; 24(3): 343 - 352.
[Abstract] [Full Text] [PDF]

Home page
 Hum ReprodHome page
A.G. Andersen, S. Ziebe, N. Jorgensen, J.H. Petersen, N.E. Skakkebak, and A. N. Andersen
Time to pregnancy in relation to semen quality assessed by CASA before and after sperm separation
Hum. Reprod., January 1, 2002; 17(1): 173 - 177.
[Abstract] [Full Text] [PDF]

Home page
 Hum ReprodHome page
C. Martinez, C. Mar, M. Azcarate, P. Pascual, J.M. Aritzeta, and A. Lopez-Urrutia
Sperm motility index: a quick screening parameter from sperm quality analyser-IIB to rule out oligo- and asthenozoospermia in male fertility study
Hum. Reprod., August 1, 2000; 15(8): 1727 - 1733.
[Abstract] [Full Text] [PDF]

Home page
 Hum ReprodHome page
British Andrology Society
British Andrology Society guidelines for the screening of semen donors for donor insemination (1999)
Hum. Reprod., July 1, 1999; 14(7): 1823 - 1826.
[Abstract] [Full Text] [PDF]

Home page
 Biol. Reprod.Home page
T. Abaigar, W. V. Holt, R. A.P. Harrison, and G. del Barrio
Sperm Subpopulations in Boar (Sus scrofa) and Gazelle (Gazella dama mhorr) Semen as Revealed by Pattern Analysis of Computer-Assisted Motility Assessments
Biol Reprod, January 1, 1999; 60(1): 32 - 41.
[Abstract] [Full Text]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.