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Human Reproduction, Vol. 10, No. 4, pp. 880-882, 1995
© 1995 European Society of Human Reproduction and Embryology

case-report

Pregnancy with spermatozoa from a globozoospermic man after intracytoplasmic sperm injection treatment

K.M. Trokoudes1,3, N. Danos1, L. Kalogirou1, R. Vlachou1, T. Lysiotis1, N. Georghiades1, S. Lerios1 and K. Kyriacou2

1‘Pedieos’ IVF Center 8 Karaoli St., Suite 201, Nicosia 162 2The Cyprus Institute of Neurology and Genetics P.O. Box 3462, Nicosia, Cyprus

Correspondence: 3To whom correspondence should be addressed

We present a case of third trimester pregnancy occurring in a 29 year old woman after intracytoplasmic sperm injection (ICSI) treatment with spermatozoa from a globozoospermic man. We believe this is the first reported case. A 37 year old man was diagnosed with globozoospermia with normal sperm count and motility. In-vitro fertilization and subzonal insemination treatments failed to achieve fertilization of any eggs. The ICSI method produced 50% fertilization, 75% cleavage rate and a singleton pregnancy with a female fetus. No pregnancy or fetal abnormalities have been noted after >7 months of gestation.

Key words: globozoospermia/CSI/infertility/normal pregnancy/transmission electron microscopy


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