Skip Navigation

This Article
Right arrow FREE Full Text (PDF ) Freely available
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Balasch, J.
Right arrow Articles by Vanrell, J. A.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Balasch, J.
Right arrow Articles by Vanrell, J. A.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Human Reproduction, Vol. 11, No. 12, pp. 2591-2594, 1996
© 1996 European Society of Human Reproduction and Embryology

research-article

Endocrinology: Midluteal immunoreactive {alpha}-inhibin serum concentrations as markers of luteal phase deficiency

Juan Balasch1,4, Montserrat Creus1, Francisco Fábregues1, Roser Casamitjana2, Jaime Ordi3 and Juan A. Vanrell1

1Department of Obstetrics and Gynecology Faculty of Medicine-University of Barcelona, Hospital Clinic I Provincial C/Casanova 143, 08036 Barcelona, Spain 2Hormonal Laboratory Faculty of Medicine-University of Barcelona, Hospital Clinic I Provincial C/Casanova 143, 08036 Barcelona, Spain 3Department of Histopathology, Faculty of Medicine-University of Barcelona, Hospital Clinic I Provincial C/Casanova 143, 08036 Barcelona, Spain

Correspondence: 4To whom correspondence should be addressed

The present prospective clinical study was undertaken to determine the usefulness of midluteal phase serum immunoreactive {alpha}-inhibin concentrations as markers of luteal phase deficiency and whether they are better indicators of biopsy confirmed luteal phase defect than serum progesterone. Consecutive patients (n = 138) with regular menstrual cycles attending our Infertility Clinic (experimental group) and 15 fertile women who were requesting contraception and had regular menstrual patterns (control group) were included. In all women (patients and controls), basal body temperature, midluteal serum concentrations of oestradiol, prolactin, progesterone and immunoreactive {alpha}-inhibin, and premenstrual endometrial biopsy were used in the same cycle to assess luteal function. Out-of-phase secretory endometria were detected in 15 of the 138 patients. Thus, hormonal concentrations were compared between the following three groups of women: group 1 (n = 15), infertile patients with defective secretory endometria; group 2 (n = 123), infertile patients with normal secretory endometria; and controls (n = 15), fertile women with normal secretory endometria. Midluteal serum concentrations of progesterone, immunoreactive {alpha}-inhibin, oestradiol, and prolactin of the two groups studied were similar to those of the control group of fertile women. Our results indicate that midluteal serum inhibin determination does not accurately reflect histological maturation of the endo-metrium and it is not a better indicator of endometrial luteal phase deficiency than midluteal serum progesterone concentration.

Key words: endometrium/luteal phase deficiency/serum inhi-bin/serum progesterone


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Hum ReprodHome page
M. Creus, J. Ordi, F. Fabregues, R. Casamitjana, J. A. Vanrell, and J. Balasch
Mid-luteal serum inhibin-A concentration as a marker of endometrial differentiation
Hum. Reprod., July 1, 2001; 16(7): 1347 - 1352.
[Abstract] [Full Text] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.