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Human Reproduction, Vol. 11, No. 6, pp. 1173-1176, 1996
© 1996 European Society of Human Reproduction and Embryology

case-report

Aorto-subclavian thromboembolism: a rare complication associated with moderate ovarian hyperstimulation syndrome

Marc Germond, Daniel Wirthner, Dominique Thorin1, Patrick Ruchat2, Axel Essinger3 and Pierre De Grandi

1Service of Anesthesiology CHUV, 1011 Lausanne, Switzerland 2Service of Cardiovascular Surgery CHUV, 1011 Lausanne, Switzerland 3Department of Radiology CHUV, 1011 Lausanne, Switzerland Fertility Unit, Department of Gynaecology and Obstetrics CHUV, 1011 Lausanne, Switzerland

The case of an arterial aorto-subclavian thromboembolism associated with a moderate ovarian hyperstimulation syndrome (OHSS) and following ovulation induction for in-vitro fertilization in a young woman is reported. Because of the lack of response to systemic thrombolysis, a left postero-lateral thoracotomy was performed on day 8 after embryo transfer. A fibrinocruoric embolus situated at the junction of the left subclavian artery from the aorta was removed through a left subclavian arteriotomy. The distal axillary embolus was removed by a retrograde balloon catheter embolectomy. A moderate OHSS was observed. The ovarian stimulation and OHSS-related risks of thromboembolism are discussed. We conclude that, in the absence of risk factors, counselling about possible complications resulting from stimulation must be emphasized.

Key words: arterial thromboembolism/IVF/menotrophin/ovarian hyperstimulation syndrome


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