Skip Navigation

This Article
Right arrow FREE Full Text (PDF ) Freely available
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Findlay, J. K.
Right arrow Search for Related Content
PubMed
Right arrow Articles by Findlay, J. K.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Human Reproduction, Vol. 11, No. suppl_2, pp. 179-183, 1996
© 1996 European Society of Human Reproduction and Embryology

Future directions for research on endometrial bleeding

J. K. Findlay

Prince Henry's Institute of Medical Research PO Box 5152, Clayton, Victoria 3168, Australia

Disturbances in endometrial bleeding remain a major problem, and the primary reason for discontinuation of progestin-only methods of contraception. However, some interesting leads were uncovered in the course of this meeting on ‘Current research on progestin-only contraceptives and endometrial bleeding’, and a number of suggestions made about techniques and research topics. This paper attempts to summarize these suggestions, with a view to stimulating further research. Topics identified included the development of objective tests for vessel fragility, identification and properties of vessels likely to bleed, the location of bleeding vessels, the basis of the increased microvascular density, the integrity of the surface epithelium, the state of the stroma, the function of steroid receptors, and the properties of progestins and oestrogens. Several animal models are discussed, including monkeys, SCID mice and steroid-treated ovariectomized mice, and potential therapeutic agents suitable for human use are identified.

Key words: animal models/clinical treatments/endometrial bleeding/research suggestions


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Hum ReprodHome page
M.-L. Alvarez Gonzalez, C. Galant, F. Frankenne, M. Nisolle, S. Labied, J.-M. Foidart, E. Marbaix, and A. Beliard
Development of an animal experimental model to study the effects of levonorgestrel on the human endometrium
Hum. Reprod., March 1, 2009; 24(3): 697 - 704.
[Abstract] [Full Text] [PDF]

Home page
 Hum ReprodHome page
K. A. Burton, T. A. Henderson, S. G. Hillier, J.I. Mason, F. Habib, R. M. Brenner, and H. O.D. Critchley
Local levonorgestrel regulation of androgen receptor and 17{beta}-hydroxysteroid dehydrogenase type 2 expression in human endometrium
Hum. Reprod., December 1, 2003; 18(12): 2610 - 2617.
[Abstract] [Full Text] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.