Skip Navigation

This Article
Right arrow FREE Full Text (PDF ) Freely available
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Hadisaputra, W.
Right arrow Articles by Rogers, P. A. W.
Right arrow Search for Related Content
PubMed
Right arrow Articles by Hadisaputra, W.
Right arrow Articles by Rogers, P. A. W.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Human Reproduction, Vol. 11, No. suppl_2, pp. 31-34, 1996
© 1996 European Society of Human Reproduction and Embryology

Endometrial biopsy collection from women receiving Norplant®

W. Hadisaputra, B. Affandi1, J. Witjaksono2 and P. A. W. Rogers3,4

Klinik Raden Saleh, J.L.Raden Saleh Raya 49, Jakarta 10430 1 Bagian Obstetri dan Ginckologi, Fakultas Kedokleran, Universitas Indonesia Jalan Raden Saleh 49, Jakarta 2 Bagian Obstetri dan Ginekologi,Fakultas Kedokteran, Universitas Indonesia Jalan Diponegoro 71, Jakarta 10430, Indonesia 3 Department of Obstetrics and Gynaecology, Monash University, Monash Medical Centre 246 Clayton Road, Clayton, 3168 Victoria, Australia

Correspondence: 4To whom correspondence should be addressed

A series of 191 endometrial biopsy procedures were performed on Indonesian women who had received between 3 and 12 months exposure to Norplant®. In all, 87 biopsy procedures were attempted with a microhysteroscope using biopsy forceps, and 104 procedures were attempted with either Pipelle or Karman suction curettes. Regardless of the biopsy method, diagnosable endometrium was obtained in only ~50% of procedures. Myometrium was often found in microhysteroscope but not in suction biopsies. An analysis of a number of clinical characteristics showed that women from whom diagnosable endometrial tissue was obtained had higher mean peripheral oestrogen concentrations hi the 2 weeks prior to biopsy (439 ± 35 versus 289 ± 33 pmol/1; P = 0.0018) and significantly more days when endometrial bleeding occurred in the 90 days prior to biopsy (26.5 ± 2.1 versus 16.2 ± 1.8; P = 0.0003). These results suggest that after 3–12 months exposure to Norplant ~50% of women have an endometrium too thin to sample, and that this group is characterized by lower peripheral oestrogen concentrations and reduced menstrual bleeding.

Key words: endometrial biopsy/Karman cannula/microhysteroscope/Norplant®/Pipelle suction curette


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Hum ReprodHome page
W. Sereepapong, P. Chotnopparatpattara, S. Taneepanichskul, R. Markham, P. Russell, and I. S. Fraser
Endometrial progesterone and estrogen receptors and bleeding disturbances in depot medroxyprogesterone acetate users
Hum. Reprod., March 1, 2004; 19(3): 547 - 552.
[Abstract] [Full Text] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.