Skip Navigation

This Article
Right arrow FREE Full Text (PDF ) Freely available
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (28)
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Halbert, S. A.
Right arrow Articles by Soules, M. R.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Halbert, S. A.
Right arrow Articles by Soules, M. R.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Human Reproduction, Vol 12, 55-58, Copyright © 1997 by Oxford University Press

ARTICLES

Function and structure of cilia in the fallopian tube of an infertile woman with Kartagener's syndrome

SA Halbert, DL Patton, PW Zarutskie and MR Soules
Department of Obstetrics and Gynecology, University of Washington, Seattle 98195-6460, USA.

In Kartagener's syndrome (KS), primary defects of the ciliary axoneme cause dyskinetic ciliary motion. Because ciliary motion is an important factor in normal ovum transport, ciliary dyskinesia may cause infertility. On the other hand, the existence of some ciliary activity, albeit abnormal, may account for fertility in some women with KS. In this case study, an infertile woman diagnosed with KS had normal results in all usual infertility tests. Biopsies of tubal mucosa were obtained at laparoscopy for ovum recovery during an in-vitro fertilization cycle. Ciliary activity, measured by laser light- scattering spectroscopy, was detected in all tubal specimens; however the majority of regions sampled showed no activity. In active regions, beat frequency ranged from 5 to 10 Hz, approximately 30% of normal. Electron microscopy showed similar morphological defects in both tubal and nasal mucosa. The number of cilia per cell was approximately 20% of normal. The major ultrastructural abnormality of cilia was an absence of the central microtubules. The only demonstrable explanation for this patient's infertility was primary ciliary dyskinesia associated with KS.
Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Arch. Dis. Child.Home page
A. Bush, R. Chodhari, N. Collins, F. Copeland, P. Hall, J. Harcourt, M. Hariri, C. Hogg, J. Lucas, H. M Mitchison, et al.
Primary ciliary dyskinesia: current state of the art
Arch. Dis. Child., December 1, 2007; 92(12): 1136 - 1140.
[Abstract] [Full Text] [PDF]

Home page
 Hum Reprod UpdateHome page
R.A. Lyons, E. Saridogan, and O. Djahanbakhch
The reproductive significance of human Fallopian tube cilia
Hum. Reprod. Update, July 1, 2006; 12(4): 363 - 372.
[Abstract] [Full Text] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.