Human Reproduction, Vol 12, 2167-2173, Copyright © 1997 by Oxford University Press
JA Stewart, PJ Hamilton and AP Murdoch
Thromboembolic disease, as a complication of ovarian stimulation and
assisted conception techniques, is generally considered to be a rare
complication of ovarian hyperstimulation syndrome and, by implication,
lower limb in origin. Sporadic cases of unusually sited thromboses, both
venous and arterial, have been reported. This paper aims to draw attention
to the relatively large number of such thromboses reported in the world
literature compared with those cited in previous commentaries, and to
emphasize how little is known about their pathogenesis. It is believed that
this is an issue which requires to be addressed in order to understand the
background pathology to such incidents and if possible to identify women at
greatest risk from such potentially debilitating or fatal complications,
such that appropriate prophylactic measures can be taken.
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Thromboembolic disease associated with ovarian stimulation and assisted conception techniques
Centre for Reproductive Medicine, Royal Victoria Infirmary, Newcastle- upon-Tyne, UK.
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