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Human Reproduction, Vol. 12, No. 11, pp. 2489-2492, 1997
© 1997 European Society of Human Reproduction and Embryology

Is a prolonged bed rest following embryo transfer useful?

Giuseppe Botta1,3 and Gedis Grudzinskas2

1 Ecocenter and Fertility Center, Clinica ‘C.G. Ruesch’ 39 via Maria Cristina di Savoia, 80122, Naples, Italy 2 Academic Department of Obstetrics and Gynaecology, St Bartholomew and Royal London Hospital, School of Medicine and Dentistry Londonc El IBB, UK

Correspondence: 3To whom correspondence should be addressed

A total of 182 infertile patients undergoing in-vitro fertilization (IVF)—embryo transfer were randomly assigned into two groups. Eighty-seven patients (group A) underwent 97 treatment cycles and had 87 embryo transfer procedures followed by a 24 h period of bed rest. Ninety-five patients (group B) underwent 102 treatment cycles and had 93 embryo transfer followed by a 20 min period of bed rest. There were no statistically significant differences seen between the groups with respect to age, duration and causes of infertility and number of previous fertility treatments. The clinical and biological procedures were identical in both groups, the only difference being the length of bed rest. There were 21 pregnancies in group A (pregnancy rate per embryo transfer: 24.1%) while in group B there were 22 (pregnancy rate per embryo transfer: 23.6%). There were four spontaneous miscarriages (19%) and three twin pregnancies (14.2%) in group A, while in group B there were four spontaneous miscarriages (18.1%) and three twin pregnancies (13.6%). None of these values was statistically significant (P > 0.05). This study shows that a 24 h period of bed rest following embryo transfer is not associated with a better outcome of the IVF–embryo transfer when compared with a 20 min rest period. Prolonged bed rest does not appear to influence the implantation rate after IVF–embryo transfer.

Key words: bed rest/embryo transfer/IVF

Submitted on February 13, 1997; accepted on August 1, 1997.


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