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Human Reproduction, Vol 12, 1021-1023, Copyright © 1997 by Oxford University Press

ARTICLES

Sertoli-Leydig cell tumour in an infertile patient after stimulated ovulation

HH Chou, YM Lai, CH Lai, S Hsueh and YK Soong
Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital, Linkou Medical Center, Taipei, Taiwan, Republic of China.

A 36 year-old infertile female developed a stage IV (FIGO) ovarian carcinoma consisting of a poorly differentiated Sertoli-Leydig cell tumour after receiving one course of ovulation induction with follicle stimulating hormone (FSH), human menopausal gonadotrophin (HMG) and human chorionic gonadotrophin (HCG) followed by gonadotrophin-releasing hormone analogue (GnRHa). The patient died of liver metastasis and hepatic failure 4 1/2 months after first diagnosis, despite aggressive treatment consisting of debulking surgery and aggressive adjuvant chemotherapy.
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