Human Reproduction, Vol 12, 1152-1155, Copyright © 1997 by Oxford University Press
YK Kim, SK Wasser, VY Fujimoto, NA Klein, DE Moore and MR Soules
The relative efficacy of follicle stimulating hormone (FSH), luteinizing
hormone (LH), FSH:LH ratio and oestradiol is evaluated as a predictor of
ovarian reserve (reproductive age) in normal women. Serum levels of FSH,
LH, oestradiol and FSH:LH ratios were measured during menstrual cycle days
1-4 in younger (20-25 years; n = 23) and older (40- 45 years; n = 32)
reproductive age women with regular menstruation and normal reproductive
function. On days 1-4, mean levels of FSH, oestradiol and FSH:LH ratios
were significantly higher in older compared with younger women. FSH
increased in concentration across cycle days in both age groups. A
significantly lower LH value in younger versus older women was found only
on day 1. Oestradiol showed no change across days in the younger group, but
increased significantly from day 1 to day 4 in the older group. FSH values
on days 1 or 2 were the best single predictor of age differences. However,
the best prediction of age differences was obtained by using the
combination of FSH and LH (as opposed to the FSH:LH ratio) on day 1 of the
menstrual cycle.
ARTICLES
Utility of follicle stimulating hormone (FSH), luteinizing hormone (LH), oestradiol and FSH:LH ratio in predicting reproductive age in normal women
Department of Obstetrics and Gynecology, University of Washington School of Medicine, Seattle 98195, USA.
CiteULike 
Connotea 
Del.icio.us What's this?
This article has been cited by other articles:
|
|
 |
|
  P. Medeiros, M. Febronio, E Bonfa, E. Borba, A. Takiuti, and C. Silva Menstrual and hormonal alterations in juvenile systemic lupus erythematosus Lupus, January 1, 2009; 18(1): 38 - 43. [Abstract] [PDF]
|
|
|
|
|
|
C.A.A. Silva, M.O. Hilario, M.V. Febronio, S.K. Oliveira, M.T. Terreri, S.B. Sacchetti, F.R. Sztajnbok, R. Marini, M.V. Quintero, B.E. Bica, et al. Risk factors for amenorrhea in juvenile systemic lupus erythematosus (JSLE): a Brazilian multicentre cohort study Lupus, July 1, 2007; 16(7): 531 - 536. [Abstract] [PDF]
|
|
|
|
 |
|
 W S. A Smellie Cases in primary care laboratory medicine: testing pitfalls and summary of guidance on sex hormone testing BMJ, January 13, 2007; 334(7584): 91 - 94. [Full Text] [PDF]
|
|
|
|
 |
|
 W S A Smellie, J Forth, S Sundar, E Kalu, C A M McNulty, E Sherriff, I D Watson, C Croucher, T M Reynolds, and P J Carey Best practice in primary care pathology: review 4 J. Clin. Pathol., September 1, 2006; 59(9): 893 - 902. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 K. Lutchman Singh, M. Davies, and R. Chatterjee Fertility in female cancer survivors: pathophysiology, preservation and the role of ovarian reserve testing Hum. Reprod. Update, January 1, 2005; 11(1): 69 - 89. [Abstract] [Full Text] [PDF]
|
|