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Human Reproduction, Vol 13, 120-123, Copyright © 1998 by Oxford University Press

ARTICLES

Detrimental effects of polyvinylpyrrolidone on the ultrastructure of spermatozoa (Notulae seminologicae 13)

E Strehler, B Baccetti, K Sterzik, S Capitani, G Collodel, M De Santo, L Gambera and P Piomboni
Institute for Reproductive Medicine, Ulm, Germany.

The effect of in-vitro treatment by polyvinylpyrrolidone (PVP) on the ultrastructure of human spermatozoa has been tested previously with the statistical analysis of B. Baccetti et al. (1995, J. Androl., 16, 356- 371). PVP had a primary detrimental action on the plasma membrane, as well as on acrosomal and mitochondrial membranes. Furthermore, membrane damage induces deterioration of the chromatin, axonemal tubules, fibrous sheath, and accessory fibres.
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