Skip Navigation

This Article
Right arrow FREE Full Text (PDF ) Freely available
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (4)
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Schwärzler, P.
Right arrow Articles by Ville, Y.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Schwärzler, P.
Right arrow Articles by Ville, Y.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Human Reproduction, Vol. 13, No. 10, 2966-2969, October 1998
© 1998 European Society of Human Reproduction and Embryology

Case report: The cobweb syndrome: first trimester sonographic diagnosis of multiple amniotic bands confirmed by fetoscopy and pathological examination

P. Schwärzler1, G. Moscoso2, M-V. Senat1, J.S. Carvalho1, D. Gould2 and Y. Ville1

1 Fetal Medicine Unit, St George's Hospital Medical School, Blackshaw Road, London SW17 0QT, UK 2 Early Human Development Research Unit, St George's Hospital Medical School, Blackshaw Road, London SW17 0QT, UK

Correspondence: To whom correspondence should be addressed

Amniotic band syndrome is a well described clinical entity presenting with deformities of the limbs, thorax, craniofacial skeleton, soft tissues and umbilical cord, but it still lacks a precise definition and a coherent hypothesis for its pathogenesis. We report on a case of first trimester diagnosis of amniotic band syndrome by sonography and fetoscopy. This revealed multiple abnormalities including facial cleft, brain and limb deformities; the appearance of the amniotic cavity was that of a cobweb containing the fetus. Postmortem examination and histopathological studies confirmed the diagnosis of amniotic band syndrome. These results may enhance the knowledge of its natural course. In addition, based on histological and newly identified ultrastructural features, we present a hypothesis which could help to explain the aetiopathogenesis of the amniotic band syndrome.

Key words: amniotic band syndrome/facial cleft/fetoscopy/limb amputation/prenatal ultrasound


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Hum ReprodHome page
J. A. Deprest, N. A. Papadopulos, H. Decaluwe, H. Yamamoto, T. E. Lerut, and E. Gratacos
Closure techniques for fetoscopic access sites in the rabbit at mid-gestation
Hum. Reprod., July 1, 1999; 14(7): 1730 - 1734.
[Abstract] [Full Text] [PDF]


Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.