Human Reproduction, Vol 13, 3351-3356, Copyright © 1998 by Oxford University Press
L Anderson, SE Lewis and N McClure
Infertility affects approximately 15% of couples, and in about one- third
the primary cause is a male factor. Patients undergoing infertility
investigations frequently experience sexual dysfunction, which often is due
to inadequate vaginal lubrication. This can lead to increased use of coital
lubricants. The effects of such lubricants on sperm motility have not been
widely studied, although sperm motility is one of the best prognostic
indicators of fertilization. Using a prospective longitudinal control-based
study, we analysed the effect of adding four lubricants: KY jelly, baby
oil, olive oil and saliva on sperm motion in 16 samples from patients
undergoing infertility investigations. Sperm samples were prepared by
density gradient centrifugation prior to mixing with lubricants. Motility
parameters were determined using computer-assisted semen analysis after 5,
15 and 30 min. All lubricants except baby oil significantly decreased
percentage progressive motility, progressive velocity, curvilinear velocity
and lateral head displacement at 12.5% concentration. At a lower
concentration of 6.25%, both olive oil and saliva still significantly
reduced progressive motility parameters, while KY jelly diminished head
movement parameters. Hence, even at these very low concentrations, coital
lubricants impair sperm motility and thus may adversely affect fertility.
ARTICLES
The effects of coital lubricants on sperm motility in vitro
Department of Obstetrics and Gynaecology, The Queen's University of Belfast, Institute of Clinical Science, UK.
![]()
CiteULike
Connotea
Del.icio.us What's this?