Human Reproduction, Vol 13, 531-534, Copyright © 1998 by Oxford University Press
I Noci, R Biagiotti, M Maggi, F Ricci, A Cinotti and G Scarselli
The aim of the present work was to evaluate whether low day 3 luteinizing
hormone (LH) values in the presence of normal follicle stimulating hormone
(FSH) are predictive of poor response to ovarian stimulation. Two groups of
women undergoing ovarian stimulation and differing only in the day 3 LH
concentration (<3 mIU/ml, study group, n=30; >3 mIU/ml, control
group, n=45) were retrospectively analysed. Study group patients developed
a lower oestradiol peak (703+/-388 versus 955+/-400 ng/ml; P = 0.005) and a
lower number of follicles >15 mm diameter at the time of human chorionic
gonadotrophin (HCG) administration (2.6+/-1.3 versus 3.6+/-1.8; P=0.004)
than the control group. Conversely, a similar ratio of oestradiol:
follicles >15 mm diameter was observed (256+/-118 versus 269+/-93;
P=0.563). The number of follicles >10 mm at the time of HCG
administration appeared to be lower in the study group, but this difference
was not statistically significant (6+/-3.9 versus 7.8+/-4.3). Our data
indicate that day 3 LH values <3 mIU/ml are predictive of poor response
to ovarian stimulation.
ARTICLES
Low day 3 luteinizing hormone values are predictive of reduced response to ovarian stimulation
Department of Obstetrics and Gynaecology, University of Florence, Italy.
CiteULike 
Connotea 
Del.icio.us What's this?
This article has been cited by other articles:
|
|
 |
|
  B. Popovic-Todorovic, A. Loft, A. Lindhard, S. Bangsboll, A.M. Andersson, and A.N. Andersen A prospective study of predictive factors of ovarian response in 'standard' IVF/ICSI patients treated with recombinant FSH. A suggestion for a recombinant FSH dosage normogram Hum. Reprod., April 1, 2003; 18(4): 781 - 787. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
N. Gleicher, M. Vietzke, and A. Vidali Bye-bye urinary gonadotrophins?: Recombinant FSH: A real progress in ovulation induction and IVF? Hum. Reprod., March 1, 2003; 18(3): 476 - 482. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J.L. Luborsky, P. Thiruppathi, B. Rivnay, R. Roussev, C. Coulam, and E. Radwanska Evidence for different aetiologies of low estradiol response to FSH: age-related accelerated luteinization of follicles or presence of ovarian autoantibodies Hum. Reprod., October 1, 2002; 17(10): 2641 - 2649. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. De Placido, A. Mollo, C. Alviggi, I. Strina, M. T. Varricchio, A. Ranieri, N. Colacurci, A. Tolino, and M. Wilding Rescue of IVF cycles by HMG in pituitary down-regulated normogonadotrophic young women characterized by a poor initial response to recombinant FSH Hum. Reprod., September 1, 2001; 16(9): 1875 - 1879. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. Filicori and G. E. Cognigni Roles and Novel Regimens of Luteinizing Hormone and Follicle-Stimulating Hormone in Ovulation Induction J. Clin. Endocrinol. Metab., April 1, 2001; 86(4): 1437 - 1441. [Abstract] [Full Text]
|
|
|
|
|
|
V. Karande and N. Gleicher A rational approach to the management of low responders in in-vitro fertilization: Opinion Hum. Reprod., July 1, 1999; 14(7): 1744 - 1748. [Full Text] [PDF]
|
|
|
|
|
|
K. Vicdan, A. Z. Isik, I. Noci, and M. Maggi Low day 3 luteinizing hormone values are predictive of reduced response to ovarian stimulation Hum. Reprod., March 1, 1999; 14(3): 863 - 864. [Full Text] [PDF]
|
|