Human Reproduction, Vol 13, 901-904, Copyright © 1998 by Oxford University Press
H Tournaye, K Clasen, A Aytoz, Z Nagy, A Van Steirteghem and P Devroey
This retrospective controlled study aimed at comparing two techniques for
recovering testicular spermatozoa in azoospermic patients undergoing
intracytoplasmic sperm injection (ICSI). 102 men suffering from infertility
because of obstructive azoospermia had ICSI using testicular spermatozoa
recovered either by open excisional biopsy (n = 51), or by fine needle
aspiration (FNA) (n = 51). A higher average number of spermatozoa were
recovered after open biopsy than after FNA, but no significant differences
in either fertilization rates or cleavage rates were observed after ICSI
with spermatozoa retrieved by the two techniques. Neither was there any
significant difference in ongoing pregnancy and implantation rates: in the
FNA group, these figures were respectively 19.6% per cycle and 7.8% per
embryo transferred and in the open biopsy group 21.6 and 7.1%. We conclude
that ICSI with testicular spermatozoa recovered by FNA yields results
comparable to those obtained with spermatozoa recovered by open biopsy in
azoospermic patients with normal spermatogenesis. However a prospective
study is needed to confirm the present results and to assess recovery rates
and patient comfort for the two methods.
ARTICLES
Fine needle aspiration versus open biopsy for testicular sperm recovery: a controlled study in azoospermic patients with normal spermatogenesis
Centre for Reproductive Medicine, University Hospital, Dutch-speaking Brussels Free University (Vrije Universiteit Brussel), Belgium.
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