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Human Reproduction, Vol. 13, No. suppl_2, pp. 35-49, 1998
© 1998 European Society of Human Reproduction and Embryology

Multicentre approaches to donor insemination in the French CECOS Federation: Nationwide evaluation, donor matching, screening for genetic diseases and consanguinity

Dominique Le Lannou1,4, François Thépot2,4 and Pierre Jouannet3,4

1 CECOS de l'Ouest, Centre Hospitalier Hotel-Dieu 1 rue de la Cochardiére, F 35000 Rennes, France 2 CECOS Picardie, Laboratoire de Biologie de la Réproduction et de Cytogenetique, Centre Hospitalier Universitaire d'Amiens 124 rue Camille Desmoulins, 80000 Amiens, France 3 CECOS, Hôpital Cochin 123 Bid de Port Royal, 75014 Paris, France

Correspondence: 4To whom correspondence can be addressed

The French CECOS Federation collates the results of its 22 sperm banks and provides annual reports on their activity. These records allow studies on many different aspects; annual nationwide evaluation, matching of donors and recipients, follow-up of pregnancies, research into artificial procreation, and natural fertility. Risk of transmitted hereditary disease is minimised by genetic screening which establishes the genealogy of donor candidates and includes karyotyping and other biological investigations when a particular risk is suspected. The real risk of consanguinity is very small. Limiting the number of children born from a given sperm donor can be defined at the local level.

Key words: consanguinity/donor insemination/frozen donor semen/genetic diseases/sperm banks


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