Skip Navigation

This Article
Right arrow FREE Full Text (PDF ) Freely available
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Gregory, L.
Right arrow Search for Related Content
PubMed
Right arrow Articles by Gregory, L.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Human Reproduction, Vol. 13, No. suppl_4, pp. 117-132, 1998
© 1998 European Society of Human Reproduction and Embryology

Ovarian markers of implantation potential in assisted reproduction

Linda Gregory

Cardiff Assisted Reproduction Unit (CARU), University Hospital of Wales NHS Trust Heath Park, Cardiff, CF4 4XW, UK

In-vitro fertilization provides evidence for the heterogeneity of human embryos; data from the UK indicating that ~90% of embryos selected for transfer fail to implant. The need to identify factors that promote implantation or markers of implantation is self-evident. There is an increasing awareness that the heterogeneity of follicles may have a significant impact on oocyte competence and embryo viability and that factors which contribute to the heterogeneity of follicles may provide markers of implantation in assisted conception. The markers of implantation described include the expression of llβ-hydroxysteroid dehydrogenase by granulosa cells in vitro; adhesion and proliferation of cumulus cells in vitro; steroidogenic activity of cumulus in vitro and perifollicular vascularity and vascular endothelial growth factors bound to granulosa and cumulus cells. These factors may provide clinically useful markers of implantation potential.

Key words: cumulus cells/follicular vascularity/implantation/ovarian marker/steroid


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?




Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.