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Human Reproduction, Vol. 14, No. 11, 2851-2854, November 1999
© 1999 European Society of Human Reproduction and Embryology

Assessment of endometrial volume by three-dimensional ultrasound prior to embryo transfer: clues to endometrial receptivity

F. Raga1,2,4, F. Bonilla-Musoles1,2, E.M. Casañ1,2, O. Klein2,3 and F. Bonilla1,2

1 Center for Obstetrics and Gynecology, 2 Department of Obstetrics and Gynecology, University of Valencia School of Medicine, Valencia, Spain and 3 Department of Genetics, Yale University School of Medicine, Connecticut, USA

The aim of the present prospective study was to obtain quantitative data on endometrial volume by three-dimensional (3D) ultrasound at the time of embryo transfer in an in-vitro fertilization programme and to assess its value in predicting endometrial receptivity. The cycles (n = 72) were classified according to endometrial volume: group A <2 ml, group B 2–4 ml, and group C >4 ml. Comparisons of the groups showed that pregnancy and implantation rates were significantly lower (P < 0.05) in the group of patients with an endometrial volume <2 ml. Furthermore, no pregnancy was achieved with an endometrial volume <1 ml. It is concluded that endometrial volume by 3D transvaginal ultrasound may become a new objective parameter by which to predict endometrial receptivity.

Key words: assisted conception/endometrial volume/reproductive performance/three-dimensional ultrasound

4 To whom correspondence should be addressed at: Center for Obstetrics and Gynecology, Pedro Aleixandre 57–7,46006-Valencia, Spain


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