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Human Reproduction, Vol. 14, No. 11, 2905-2907, November 1999
© 1999 European Society of Human Reproduction and Embryology

Twin pregnancy with a complete hydatidiform mole and co-existing fetus following in-vitro fertilization: Case report

Francisco Montes-de-Oca-Valero1, Lena Macara1,3 and Adel Shaker2

1 The Queen Mother's Hospital, Yorkhill, Glasgow G3 8SJ and 2 Ross Hall Hospital, Glasgow, UK

Hydatidiform mole with a co-existing live fetus is a rare event. We report the case of a 41 year old Caucasian woman who attended for in-vitro fertilization. Three embryos, containing two apparently normal pronuclei, were transferred into the uterus. A twin pregnancy with a live fetus and a complete mole ensued. The pregnancy was managed conservatively until 28 weeks gestation when, following an episode of major antepartum haemorrhage, a live female infant was delivered by Caesarean section. The mole, weighing over 1.7 kg, was successfully evacuated. Following delivery, serum human chorionic gonadotrophin concentrations returned to baseline and remain within the normal range at 24 months. Both mother and daughter are well on assessment 24 months later.

Key words: HCG/in-vitro fertilization/molar pregnancy/placenta/twin pregnancy

3 To whom correspondence should be addressed


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