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Human Reproduction, Vol. 14, No. 4, 1122-1126, April 1999
© 1999 European Society of Human Reproduction and Embryology

Delivery of a severely anaemic fetus after partial molar pregnancy: clinical and ultrasonographic findings

C.C. Hsieh1,3, T.T. Hsieh1, C. Hsueh2, D.M. Kuo1, L.M. Lo1 and T.H. Hung1

1 Maternal–Fetal Medicine, Department of Obstetrics and Gynecology, 2 Department of Pathology, Chang Gung Memorial Hospital and Medical School of Chang Gung University, Taipei, Taiwan, Republic of China

The incidence of a normal live fetus and a partial molar placenta is extremely rare. Although triploidy is the most frequent association, a fetus with normal karyotype can survive in cases of partial molar pregnancy. We report a case of partial molar placenta in which a live female baby was delivered at 32 weeks gestation by a 30-year-old woman. At the 18th week, ultrasonographic examination revealed a normal fetus with a huge, multicystic placenta. Chromosomal evaluation by amniocentesis revealed a normal female karyotype (46,XX), and serial biometric measurement of the fetus showed normal growth during pregnancy. There were no obstetric complications until the 32nd gestational week when preterm rupture of the membranes occurred. The electronic fetal heart beat tracing showed a repeated sinusoid pattern and late deceleration after admission. The patient underwent emergency Caesarean section and delivered a 1551-g, anaemic female baby with an Apgar score of 1, 4 and 6 at 1, 5 and 10 min, respectively. The baby recovered within 2 weeks after respiratory support and transfusion of packed red blood cells. Although anaemia is one of the risk factors that jeopardize the fetus in the case of partial molar pregnancy, termination is not indicated when the fetus is normal and no complications have occurred.

Key words: ß-human chorionic gonadotrophin/electronic fetal monitoring/fetal anaemia/partial molar pregnancy/ultrasound

3 To whom correspondence should be addressed at: Maternal–Fetal Medicine, Department of Obstetrics and Gynecology, 199 Tun Hwa North Road, Taipei 105 Taiwan, Republic of China


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