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Human Reproduction, Vol. 15, No. 11, 2411-2414, November 2000
© 2000 European Society of Human Reproduction and Embryology

Birth of rhesus monkey infant after transfer of embryos derived from in-vitro matured oocytes: Short communication

R.Dee Schramm1 and Ann Marie Paprocki

Wisconsin Regional Primate Research Center, University of Wisconsin, Madison, Wisconsin, USA

Although strategies for in-vitro maturation of oocytes from rodents and domestic species have been relatively successful, application of these techniques to primates has not met with similar success. Currently, evaluation of the developmental capacity of oocytes following fertilization is the only reliable means to assess cytoplasmic maturation. Although rhesus monkey blastocysts have previously been produced from in-vitro matured oocytes, full developmental competence has not been demonstrated by term development. Here we report the birth of the first non-human primate infant derived from in-vitro matured oocytes.

Key words: embryo transfer/in-vitro fertilization/in-vitro maturation/oocyte/rhesus monkey infant

1 To whom correspondence should be addressed at: Wisconsin Regional Primate Research Center, 1223 Capitol Court, Madison, WI 53715, USA. E-mail: schramm{at}primate.wisc.edu


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