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Human Reproduction, Vol. 16, No. 1, 102-106, January 2001
© 2001 European Society of Human Reproduction and Embryology

Obstetric and neonatal outcome in women with a history of recurrent miscarriage: a cohort study

S. Jivraj1, B. Anstie1, Y-C. Cheong1, F.M. Fairlie1, S.M. Laird2 and T.C. Li1,3

1 Jessop Hospital for Women and 2 Division of Biomedical Sciences, Sheffield Hallam University, Sheffield, UK

Obstetric and neonatal outcomes of women who had a history of recurrent miscarriage were compared with a control population from 1 January 1992 to 30 June 1998. Amongst a total of 162 pregnancies which progressed beyond 24 weeks gestation in women with a history of recurrent miscarriage, there were four perinatal deaths and 16 babies were admitted to the special care baby unit. The rates of preterm delivery (13%), small-for-gestational-age (13%), perinatal loss (2.5%) and Caesarean section (36%) were significantly (P < 0.05) higher than those of the control group (3.9, 2.1, 1 and 16.7% respectively). The ratio of male to female babies was equal. There was no significant difference in the incidence of hypertension or diabetes between the two groups. Patients with recurrent miscarriage represent a population at high risk of obstetric problems and close surveillance in the antenatal period is therefore required.

Key words: growth retardation/perinatal outcome/pre-eclampsia/recurrent miscarriage

3 To whom correspondence should be addressed at: Jessop Hospital for Women, Sheffield S3 7RE, UK.


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