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Human Reproduction, Vol. 16, No. 11, 2295-2297, November 2001
© 2001 European Society of Human Reproduction and Embryology

Conscious sedation versus general anaesthesia for minilaparoscopic gamete intra-Fallopian transfer: a prospective randomized study

Massimiliano Pellicano1,2,4, Fulvio Zullo2,3, Agnese Fiorentino2, Giovanni A. Tommaselli1, Stefano Palomba1,3 and Carmine Nappi1

1 Department of Obstetrics, Gynecology and Reproductive Medicine, University of Naples ‘Federico II’, 2 Endogyn and Infertility Service, Private Gynecologic Associates, Naples and 3 Department of Gynecologic and Pediatric Sciences, University of Catanzaro, Catanzaro, Italy

BACKGROUND: Gamete intra-Fallopian transfer (GIFT) is a successful technique for infertile women, and is performed almost exclusively by laparoscopy under general anaesthesia. METHODS: We performed a prospective randomized study of 67 infertile patients to assess the efficacy of minilaparoscopic GIFT under conscious sedation/local anaesthesia (group A) compared with general anaesthesia (group B). Operative and discharge times and pregnancy outcome were evaluated in both groups. RESULTS: Operative time was similar in both groups. The rate of patients discharged 2 h after surgery was significantly higher in group A. The necessity for postoperative analgesics was significantly higher in group B. No significant differences were noted between the two study groups in terms of pregnancy outcome. CONCLUSIONS: Conscious sedation and local anaesthesia will allow us to perform an outpatient minilaparoscopic GIFT without the need for general anaesthesia. The simplicity of the method, and the quicker discharge time in comparison with general anaesthesia, offer a detectable benefit for patients.

Key words: bupivacaine/conscious sedation/GIFT/local anaesthesia/minilaparoscopy

4 To whom correspondence should be addressed at: Dipartimento di Ginecologia, Ostetricia e Fisiopatologia della Riproduzione Umana, Università di Napoli ‘Federico II’, Via Pansini, 5, 80131 Napoli, Italy. E-mail: pellican{at}unina.it


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M. Guida, M. Pellicano, F. Zullo, G. Acunzo, G. Lavitola, S. Palomba, and C. Nappi
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