Human Reproduction, Vol. 16, No. 11, 2418-2421,
November 2001
© 2001 European Society of Human Reproduction and Embryology
Prevalence and risk factors of adenomyosis at hysterectomy
1 Department of Obstetrics and Gynaecology and 2Department of Pathology, Gentofte University Hospital, Niels Andersens Vej 65, 2 900 Hellerup, Denmark
BACKGROUND: The present study was performed to evaluate the prevalence and possible associated risk factors for adenomyosis. METHODS: Medical records were retrieved and histo-pathological material re-examined for 549 consecutive women undergoing hysterectomy in a two-year period from 1990–1991. RESULTS: The prevalence of adenomyosis in the study varied from 10.0–18.2%, depending on different diagnostic criteria. The presence of endometrial hyperplasia at the time of hysterectomy was the only variable significantly associated with adenomyosis (OR = 3.0; 95% CI: 1.2–8.3). No statistically significant association was found between adenomyosis and previous caesarean section, endometrial curettage or evacuation of the uterus. Furthermore, we did not see any significant association between adenomyosis and pain-related symptoms, indication for hysterectomy, age, parity or number of myometrial samples. CONCLUSIONS: Our study stresses the need for precise diagnostic criteria for adenomyosis, and furthermore indicates that endometrial hyperplasia and adenomyosis may have a common aetiology.
Key words: adenomyosis/prevalence/risk factors
3 To whom correspondence should be addressed. E-mail: tbe{at}dadlnet.dk
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