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Human Reproduction, Vol. 16, No. 4, 782-784, April 2001
© 2001 European Society of Human Reproduction and Embryology

Three blastocyst stage embryo transfer resulting in a quintuplet pregnancy: Case report

Kayhan Yakín1,3, Semra Kahraman1 and Sedat Cömert2

1 Istanbul Memorial Hospital Reproductive Endocrinology and ART Unit, Istanbul and 2 Sevgi Hospital, Perinatalogy Unit, Ankara, Turkey

High-order pregnancies are associated with high morbidity and mortality and the incidence is increased as a drastic complication of assisted reproductive technology. This case presents a high-order pregnancy achieved by transfer of three blastocyst stage embryos resulting in a quintuplet pregnancy including a monochorionic triplet. Following the selective termination of the monochorionic triplet, two healthy children were born. The mechanism of monochorionic development and its association with assisted reproductive technology are discussed.

Key words: blastocyst transfer/ICSI/multiple pregnancy/ovarian stimulation/quintuplets

3 To whom correspondence should be addressed at: Istanbul Memorial Hospital, ART and Reproductive Endocrinology Unit, Piyale Pasa Bulvari, 80270, Okmeydani, Istanbul/Turkey. E-mail: kyakin{at}hotmail.com


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K. Zikopoulos, P. Platteau, E. Kolibianakis, C. Albano, A. Van Steirteghem, and P. Devroey
Quintuplet pregnancy following transfer of two blastocysts: Case report
Hum. Reprod., February 1, 2004; 19(2): 325 - 327.
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