Human Reproduction, Vol. 16, No. 6, 1135-1139,
June 2001
© 2001 European Society of Human Reproduction and Embryology
Prophylactic salpingectomy does not impair the ovarian response in IVF treatment
1 Department of Obstetrics and Gynaecology, Sahlgrenska University hospital, S-413 45 Göteborg, Sweden, 2 The Fertility Clinic, Copenhagen University hospital, Rigshospitalet, Blegdamsvej 9, DK-2100 Copenhagen, Denmark and 3 IVF Center Falun, Falu hospital, S-791 82 Falun, Sweden
To examine the effect of prophylactic salpingectomy in patients with hydrosalpinges on the ovarian response to stimulation prior to IVF, 26 patients were included in a study in which they acted as their own controls. They were all part of a randomized controlled study, in which they had been randomized to no surgical intervention prior to IVF. After one or two failed cycles, they underwent laparoscopic uni- or bilateral salpingectomy of their diseased tubes. The cycles before and after surgery were compared and the ovarian response was assessed as the dose and duration of gonadotrophins and the number of retrieved and fertilized oocytes. There were no significant differences in any of the measured outcomes. The increasing age between cycles did not influence the ovarian response, assessed by a comparison with two matched control groups from the same original study; 46 patients salpingectomized before IVF and 25 patients without surgery. It is concluded that removal of hydrosalpinx as a prophylactic laparoscopic procedure does not compromise ovarian function.
Key words: hydrosalpinx/IVF/ovarian response/salpingectomy
4 To whom correspondence should be addressed. E-mail: annika.strandell{at}medfak.gu.se
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