Human Reproduction, Vol. 17, No. 1, 201-206,
January 2002
© 2002 European Society of Human Reproduction and Embryology
Quantification of Doppler signal in polycystic ovary syndrome using three-dimensional power Doppler ultrasonography: a possible new marker for diagnosis
1 Department of Obstetrics and Gynaecology, National Cheng Kung University Hospital and 2 Institute of Behavioural Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan
BACKGROUND: Differences in the ovarian stromal blood flow of women embarking on an IVF treatment, as assessed on day 2 or 3 of the menstrual cycle, using three-dimensional (3D) power Doppler ultrasonography to quantify the blood flow and vascularization, were compared. METHODS: The women were divided into two groups: group 1, 54 women with regular, ovulatory menstrual cycles and normal ovaries on ultrasound scan; and group 2, 25 women with polycystic ovary syndrome (PCOS). RESULTS: The quantification of Doppler signal in the ovarian stroma appeared to be greater in the PCOS group compared with the normal group. The mean of ovarian volume was significantly higher (P < 0.05) in women with PCOS compared with the normal ovaries. The vascularization flow index (VFI), flow index (FI), and vascularization index (VI), were significantly higher (P < 0.05) in the women with PCOS compared with the women with normal ovaries. CONCLUSIONS: This observation may help to explain the excessive response often seen during gonadotrophin administration in women with PCOS. We believe that a quantification study of the vascular flow, including the VI, FI, and VFI of the entire ovarian stroma using 3D power Doppler, is more accurate than the previously reported quantification analysis using 2D imaging, and may be a new parameter to assist in the ultrasound diagnosis of PCOS.
Key words: ovarian stroma/PCOS/power Doppler/stromal blood flow/three-dimensional ultrasound
3 To whom correspondence should be addressed at: Department of Obstetrics and Gynaecology, National Cheng Kung University Hospital, 138 Victory Road, Tainan 70428, Taiwan. E-mail: fchang{at}mail.ncku.edu.tw
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