Skip Navigation

This Article
Right arrow Full Text Freely available
Right arrow FREE Full Text (PDF ) Freely available
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (8)
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Delvigne, A.
Right arrow Articles by Rozenberg, S.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Delvigne, A.
Right arrow Articles by Rozenberg, S.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Human Reproduction, Vol. 17, No. 8, 1994-1996, August 2002
© 2002 European Society of Human Reproduction and Embryology

Metabolic characteristics of women who developed ovarian hyperstimulation syndrome

Annick Delvigne1,5, Karol Kostyla1, Anne De Leener2, Bernard Lejeune3, Brigitte Cantiniaux1, Pierre Bergmann4 and Serge Rozenberg1

1 Departments of Obstetrics and Gynaecology, IVF and Haematology, St Pierre University Hospital, Free University of Brussels, Rue Haute, 322, 1000 Brussels, 2 Department of Medical Genetics and Institute of Interdisciplinary Research, Faculty of Medicine, Free University of Brussels, 1070 Brussels, 3 IVF Center, Institut Médical E. Cavell, Rue Edith Cavell 32, 1080 Brussels and 4 Department of Clinical Chemistry, University Hospital Brugmann, 4 Place Van Gehuchten, Free University of Brussels, 1020 Brussels, Belgium

BACKGROUND: The aim of this study was to investigate whether a higher incidence of hyperinsulinism is found in women who have suffered from ovarian hyperstimulation syndrome (OHSS) as compared with other IVF patients. Additionally, we also assessed whether any abnormalities in the haemostatic system were more frequent in women with a past history of OHSS. METHODS: A pilot study was carried out involving OHSS patients and matched IVF patients. Homeostasis model assessment (HOMA) of insulin sensitivity was calculated. The main outcome measures were: insulin sensitivity, coagulation anomalies, factor V Leiden mutations, methylene tetrahydrofolate reductase (MTHFR) polymorphism and prothrombin gene mutation, protein C and protein S deficiency. RESULTS: No increased incidence in hyperinsulism nor in abnormalities of the haemostatic system were observed. CONCLUSIONS: This pilot study does not provide evidence for an increased prevalence of hyperinsulinism among women who have developed OHSS in the past.

Key words: insulin resistance/IVF/ovarian hyperstimulation syndrome (OHSS)

5 To whom correspondence should be addressed. E-mail: annickdelvigne{at}swing.be


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Endocr. Rev.Home page
N. S. Macklon, R. L. Stouffer, L. C. Giudice, and B. C. J. M. Fauser
The Science behind 25 Years of Ovarian Stimulation for in Vitro Fertilization
Endocr. Rev., April 1, 2006; 27(2): 170 - 207.
[Abstract] [Full Text] [PDF]

Home page
 Hum ReprodHome page
A. Wiser, J. Levron, D. Kreizer, R. Achiron, A. Shrim, E. Schiff, J. Dor, and A. Shulman
Outcome of pregnancies complicated by severe ovarian hyperstimulation syndrome (OHSS): a follow-up beyond the second trimester
Hum. Reprod., April 1, 2005; 20(4): 910 - 914.
[Abstract] [Full Text] [PDF]

Home page
 Hum ReprodHome page
T. Saisto, A. Tiitinen, V.-M. Ulander, and R. Kaaja
Clinical cure of severe, early onset preeclampsia with low molecular weight heparin therapy in primigravida with hyperreactio luteinalis and thrombophilia
Hum. Reprod., March 1, 2004; 19(3): 725 - 728.
[Abstract] [Full Text] [PDF]

Home page
 Hum ReprodHome page
Y.-C. Ou, Y.-L. Kao, S.-L. Lai, F.-T. Kung, F.-J. Huang, S.-Y. Chang, and C.-C. ChangChien
Thromboembolism after ovarian stimulation: successful management of a woman with superior sagittal sinus thrombosis after IVF and embryo transfer: Case report
Hum. Reprod., November 1, 2003; 18(11): 2375 - 2381.
[Abstract] [Full Text] [PDF]


Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.