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Human Reproduction, Vol. 18, No. 12, 2562-2564, December 2003
© 2003 European Society of Human Reproduction and Embryology

Successful pregnancy outcome following 19 consecutive miscarriages: Case report

Siobhan Quenby1,4, Roy Farquharson3, Michelle Young1 and Gill Vince2

Departments of 1 Obstetrics and Gynaecology and 2 Immunology, University of Liverpool, Liverpool L69 3BX and 3 Liverpool Women’s Hospital, Crown Street, Liverpool L8 7SS, UK

4 To whom correspondence should be addressed. e-mail: squenby{at}liv.ac.uk

No cause can be found in 50% of patients with recurrent miscarriage. Recent research has shown that high levels of natural killer (NK) cells within the endometrium may be associated with idiopathic recurrent miscarriage. This case report describes a patient in whom an excessive number of uterine NK cells were found. She received preconceptual prednisolone and delivered a live baby. This is a novel observation of untested significance.

Key words: case report/natural killer cells/prednisolone/recurrent miscarriage


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