Skip Navigation

This Article
Right arrow Full Text Freely available
Right arrow FREE Full Text (PDF ) Freely available
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (1)
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Nakauchi-Tanaka, T.
Right arrow Articles by Yoshikawa, H.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Nakauchi-Tanaka, T.
Right arrow Articles by Yoshikawa, H.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Human Reproduction, Vol. 18, No. 3, 506-508, March 2003
© 2003 European Society of Human Reproduction and Embryology

Acquired haemophilia due to factor VIII inhibitors in ovarian hyperstimulation syndrome: Case report

Tomoko Nakauchi-Tanaka1, Satoshi Sohda1,3, Katsumi Someya1, Keiko Kono2, Hiromi Hamada1 and Hiroyuki Yoshikawa1

1 Department of Obstetrics and Gynecology, Institute of Clinical Medicine, University of Tsukuba, 1–1-1 Tennodai, Tsukuba, Ibaraki 305 and 2 Departments of Obstetrics and Gynecology, Metropolitan Aoyama Hospital, 5–53–3 Jingumae, Shibuya-ku, Tokyo 150–0001, Japan

3 To whom correspondence should be addressed. e-mail: sato{at}sohda.com

A 31-year-old nulligravida woman developed an acquired factor VIII inhibitor associated with severe ovarian hyperstimulation syndrome (OHSS). She developed haematouria, ecchymosis, and intramuscular bleeding following the severe OHSS. Laboratory examinations showed a markedly prolonged activated partial thromboplastin time and a low level of factor VIII activity. Treatment with prothrombin complex concentrate and factor VIII inhibitor bypassing agent was successful in reducing the inhibitor so that she delivered a healthy baby via spontaneous vaginal delivery. Acquired haemophilia is a life-threatening disorder. This is the first case report of acquired haemophilia in OHSS.

Key words: acquired haemophilia/assisted conception/factor VIII inhibitor/OHSS


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Hum ReprodHome page
E. Jost, P. Kiefer, J. Neulen, O. Galm, and R. Osieka
Post-partum acquired haemophilia after IVF without recurrence during a second pregnancy obtained by IVF
Hum. Reprod., August 1, 2007; 22(8): 2348 - 2349.
[Full Text] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.