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Human Reproduction, Vol. 18, No. 4, 844-848, April 2003
© 2003 European Society of Human Reproduction and Embryology

Fertility and pregnancy outcomes following hypogastric artery ligation for severe post-partum haemorrhage

J. Nizard1, L. Barrinque1, R. Frydman1 and H. Fernandez1,2

1 Service de Gynécologie-Obstérique et Biologie de la Reproduction, Hôpital Antoine Béclère (AP-HP), Clamart cedex, France

2 To whom correspondence should be addressed at: Service de Gynécologie-Obstérique et Biologie de la Reproduction Hôpital Antoine Béclère (AP-HP), 157, Rue de la Porte de Trivaux, 92140 Clamart cedex, France. e-mail: herve.fernandez{at}abc.ap-hop-paris.fr

BACKGROUND: Hypogastric artery ligation is a therapeutic option for severe post-partum haemorrhage. Little is known about the outcomes of subsequent fertility and pregnancy. We studied these parameters in women who required hypogastric artery ligation for severe post-partum haemorrhage in our institution over a 13-year period. METHODS: All patients who required hypogastric artery ligation for severe intractable post-partum haemorrhage from January, 1989 to April, 2001 were included. Data were retrieved from medical files and telephone interviews. RESULTS: A total of 68 patients required hypogastric artery ligation during the study period. Seventeen patients had 21 pregnancies with 13 term deliveries, two ectopic pregnancies, three miscarriages, and three abortions. Twenty-eight patients did not want a new pregnancy and one patient refused the interview. Twenty-three (34%) patients were lost to follow up. None of the patients suffered subsequent infertility and pregnancy was achieved in <12 months once planned. Pregnancy outcomes were normal. Fifty-four percent had vaginal deliveries. Three patients suffered a threatened post-partum haemorrhage that was easily treated medically. CONCLUSIONS: This is the largest reported series of pregnancies following hypogastric artery ligation. Hypogastric artery ligation for post-partum bleeding >1 l appears to be a safe procedure that does not impair subsequent fertility and pregnancy outcomes.

Key words: fertility/hypogastric artery ligation/post-partum haemorrhage/pregnancy


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