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Human Reproduction, Vol. 18, No. 6, 1319-1322, June 2003
© 2003 European Society of Human Reproduction and Embryology

Normal birth after microsurgical enucleation of tripronuclear human zygotes: Case report

Suresh Kattera1 and Christopher Chen

Centre for Reproductive Medicine and Gleneagles IVF Centre, Singapore 258500

1 To whom correspondence should be addressed. e-mail: kattera{at}singnet.com.sg

Microsurgical enucleation of a single pronucleus from each of three tripronuclear zygotes was performed and the embryos were transferred to a 38-year-old woman on day 3 after fertilization. A normal healthy baby boy was born at 38 weeks and 4 days gestation, demonstrating that with polyspermic fertilization, removal of the extra male pronucleus allows the zygote to develop normally.

Key words: embryos/enucleation/male pronuclei/oocytes/tripronuclear zygotes


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