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Human Reproduction, Vol. 19, No. 2, 328-329, February 2004
© 2004 European Society of Human Reproduction and Embryology

Twin delivery following 12 years of human embryo cryopreservation: Case report

A. Revel1, A. Safran, N. Laufer, A. Lewin, B.E. Reubinov and A. Simon

In Vitro Fertilization Unit, Department of Obstetrics and Gynecology, Hadassah University Hospital, Ein Kerem, PO Box 12000, Jerusalem 91120, Israel

1 To whom correspondence should be addressed. e-mail: Revel{at}md.huji.ac.il

It is uncertain how long IVF units can keep frozen embryos. Few data exist on success of embryo transfer for embryos that have been cryopreserved for many years. We report the delivery of healthy twins following the transfer of embryos cryopreserved for 12 years. To the best of our knowledge, this is the longest reported successful human embryo freezing.

Key words: assisted reproductive techniques/cryopreservation/frozen embryo/IVF/multiple pregnancy


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