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Hum. Reprod. Advance Access originally published online on January 29, 2004
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Human Reproduction, Vol. 19, No. 3, 490-503, March 2004
© 2004 European Society of Human Reproduction and Embryology

Assisted reproductive technology in Europe, 2000. Results generated from European registers by ESHRE

The European IVF-monitoring programme (EIM) for the European Society of Human Reproduction and Embryology (ESHRE)1

Report prepared by A. Nyboe Andersen, L. Gianaroli and K.G. Nygren

1 Address for correspondence: ESHRE Central Office, Meerstraat 60, B-1852 Grimbergen, Belgium. e-mail: bruno.vandeneede{at}eshre.com

European results of assisted reproductive techniques from treatments initiated during 2000 are presented in this fourth annual report. Data were collected mainly from pre-existing national registers. From 22 countries, 569 clinics reported 279 267 cycles: IVF 126 961, ICSI 99 976, frozen embryo replacement (FER) 45 800 and oocyte donations (OD) 6530. In nine countries where all clinics reported to the register, a total of 142 174 cycles were performed in a population of 166 million, corresponding to 856 cycles per million inhabitants. After IVF and ICSI, the distribution of transfer of one, two, three and ≥4 embryos was 12.1, 46.7, 33.3 and 6.8%, respectively. Huge differences existed between countries. For IVF, the clinical pregnancy rate per aspiration and per transfer was 24.7 and 28.4%, respectively. For ICSI, the corresponding rates were 26,6% and 28,7%. These figures represent increases of 0.7 and 0.8% compared with 1999. The distribution of singleton, twin, triplet and quadruplet deliveries for IVF and ICSI combined was 73.6, 24.4, 2.0 and 0.04%. This gives a total multiple delivery rate of 26.4%. The range of triplet deliveries after IVF and ICSI ranged from 0.3 to 7.0% between countries. Compared with 1999, the number of reported cycles was increased by 8% and the clinical pregnancy rate per transfer was increased by 0.7% after IVF and by 0.8% after ICSI. The total multiple delivery rates after IVF and ICSI remain unchanged during the last 4 years.

Key words: ESHRE/Europe/ICSI/IVF/register data

* EIM Committee: Chairman, K.G.Nygren; co-ordinator, A.Nyboe Andersen; member L.Gianaroli. See Appendix for contributing centres and contacts representing the data collection programmes in the participating European countries.


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