Skip Navigation


Hum. Reprod. Advance Access originally published online on June 30, 2004
Human Reproduction 2004 19(9):2091-2096; doi:10.1093/humrep/deh401
This Article
Right arrow Full Text Freely available
Right arrow FREE Full Text (PDF ) Freely available
Right arrow All Versions of this Article:
19/9/2091    most recent
deh401v1
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (15)
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Choudhary, M.
Right arrow Articles by Murdoch, A.P.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Choudhary, M.
Right arrow Articles by Murdoch, A.P.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Human Reproduction vol. 19 no. 9 © European Society of Human Reproduction and Embryology 2004; all rights reserved

Demographic, medical and treatment characteristics associated with couples’ decisions to donate fresh spare embryos for research

M. Choudhary1,4, E. Haimes2, M. Herbert1, M. Stojkovic3 and A.P. Murdoch1

1 Newcastle Fertility Centre at Life, Bioscience Centre, International Centre for Life, Newcastle upon Tyne, NE1 4EP, 2 PEALS, Bioscience Centre, International Centre for Life, Newcastle upon Tyne NE1 4EP and 3 Institute of Human Genetics, University of Newcastle upon Tyne, International Centre for Life, Newcastle upon Tyne NE1 4BZ, UK

4 To whom correspondence should be addressed. Email: meenakshi.choudhary{at}newcastle.ac.uk

BACKGROUND: Isolation of human embryonic stem cell lines has opened a promising and pioneering area of basic and applied medical research. The issues in relation to a couple' decision in donating their supernumerary embryos for research need to be investigated further. METHODS: We carried out a prospective study of 300 couples who underwent IVF/ICSI treatment cycles in our unit. We analysed various factors contributing to their decision to consent to donate spare embryos for stem cell or preimplantation genetic diagnosis research. RESULTS: The majority of couples (54%) consented to donate their surplus embryos for research. Couples of ethnic minority origin were less willing to consent for research compared to Caucasian couples. The number of ovarian follicles at pre-hCG scan and the number of embryos obtained were significantly higher in couples consenting for research. The funding source of treatment did not appear to influence the decision to donate. Couples with previous failed fertilization were less likely to consent to embryo research. CONCLUSIONS: Physical characteristics based on ovarian response during a treatment cycle may positively influence a couple's decision to donate embryos. Further studies are needed to identify those couples who are likely to agree to research so that counselling for research can be directed efficiently.

Key words: consent/decision/embryonic stem cells/embryo research/human


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Clin EthicsHome page
S Devaney
Breaches in good regulatory practice - the HFEA policy on compensated egg sharing for stem cell research
Clin Ethics, March 1, 2008; 3(1): 20 - 24.
[Abstract] [Full Text] [PDF]

Home page
 Stem CellsHome page
A. J. French, C. A. Adams, L. S. Anderson, J. R. Kitchen, M. R. Hughes, and S. H. Wood
Development of Human Cloned Blastocysts Following Somatic Cell Nuclear Transfer with Adult Fibroblasts
Stem Cells, February 1, 2008; 26(2): 485 - 493.
[Abstract] [Full Text] [PDF]

Home page
 Stem CellsHome page
M. Choudhary, X. Zhang, P. Stojkovic, L. Hyslop, G. Anyfantis, M. Herbert, A. P. Murdoch, M. Stojkovic, and M. Lako
Putative Role of Hyaluronan and Its Related Genes, HAS2 and RHAMM, in Human Early Preimplantation Embryogenesis and Embryonic Stem Cell Characterization
Stem Cells, December 1, 2007; 25(12): 3045 - 3057.
[Abstract] [Full Text] [PDF]


Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.