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Human Reproduction, Vol. 2, No. 7, pp. 545-547, 1987
© 1987 European Society of Human Reproduction and Embryology

research-article

Ultrasound measurement of endometrial thickness on different ovarian stimulation regimens during in-vitro fertilization

D.A.G. Imoedemhe, R.W. Shaw1, A. Kirkland and R. Chan2

Academic Department of Obstetrics and Gynaecology London, NW3 2QG, UK 2Ultrasound Unit, Royal Free Hospital London, NW3 2QG, UK

Correspondence: 1To whom correspondence should be addressed

Endometrial thickness was measured ultrasonographically in three groups of patients undergoing in-vitro fertilization (IVF) on three different ovulation induction regimens. The endometrial thickness was comparable on all three regimens and similar to that observed in a group of spontaneously ovulating, normal, fertile controls. These patterns of endometrial thickness were observed despite significantly higher levels of serum oestradiol-17{beta} In all of the hyperstimulated cycles, suggesting that in the normal cyde a maximum response in terms of endometrial development may be achieved. In the three conception cycles endometrial thickness continued to increase throughout the luteal phase, whilst In non-conception cycles plateauing of thickness increase occurred in the mid-luteal phase and reduction in late luteal phase. Whether ultrasonographic evaluation of endometrium during IVF stimulation cydes has any prognostic value regarding prediction of conception has yet to be detennined.

Key words: endometrial thickness/ultrasound/ovarian stimulation/IVF


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