Hum. Reprod. Advance Access originally published online on January 21, 2005
Human Reproduction 2005 20(5):1158-1176; doi:10.1093/humrep/deh755
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Eshre Pages |
Assisted reproductive technology in Europe, 2001. Results generated from European registers by ESHRE
Report prepared by A Nyboe Andersen, L.Gianaroli, R. Felberbaum, J. de Mouzon and K.G.NygrenThe European IVF-monitoring programme (EIM) , for the European Society of Human Reproduction and Embryology (ESHRE)1,2
European results of assisted reproductive techniques from treatments initiated during 2001 are presented in this fifth report. Data were collected mainly from already existing national registers. From 23 countries, 579 clinics reported 289 690 cycles with: IVF 120 946, ICSI 114 378, frozen embryo transfer (FER) 47 195 and egg donation (ED) 7171. Overall this represents a 4% increase since the year 2000. For the first time, results on European data on intra-uterine inseminations (IUIs) were reported from 15 countries. A total of 67 124 cycles [IUI husband'sperm (IUI-H) 52 949 and IUI donor sperm (IUI-D) 14 185] were included. In 12 countries where all clinics reported to the register, a total of 108 910 cycles were performed in a population of 131.4 million, corresponding to 829 cycles per million inhabitants. For IVF, the clinical pregnancy rate per aspiration and per transfer was 25.1 and 29.0%, respectively. For ICSI, the corresponding rates were 26.2 and 28.3%. These figures are similar to the results from 2000. After IUI-H, the clinical pregnancy rate was 12.8% in women <40 and 9.7% in women 
40 years of age. After IVF and ICSI, the distribution of transfer of one, two, three and 4 embryos was 12.0, 51.7, 30.8 and 5.5%, respectively. Compared with the year 2000, fewer embryos were transferred, but huge differences existed between countries. The distribution of singleton, twin and triplet deliveries for IVF and ICSI combined was 74.5, 24.0 and 1.5%, respectively. This gives a total multiple delivery rate of 25.5%, compared with 26.9% in the year 2000. The range of triplet deliveries after IVF and ICSI differed from 0.0 to 8.2% between countries. After IUI-H in women <40 years of age, 10.2% were twin and 1.1% were triplet gestations.
Key words: Europe/ICSI/IUI/IVF/register data
1EIM Committee: Chairman, K.G.Nygren; co-ordinator, A. Nyboe Andersen; member L.Gianaroli, R.Felberbaum and J.de Mouzon. See Appendix for contributing centres and contact persons representing the data collection programmes in the participating European countries.
2Address for correspondence: ESHRE Central Office, Meerstraat 60, B-1852 Grimbergen, Belgium.bruno.vandeneede{at}eshre.com
CiteULike 
Connotea 
Del.icio.us What's this?
This article has been cited by other articles:
|
|
 |
|
  M A Luque Fernandez, A B. Cavanillas, M Dramaix-Wilmet, F S Soria, J de Mata Donado Campos, and D H Guibert Increase in maternal mortality associated with change in the reproductive pattern in Spain: 1996-2005 J Epidemiol Community Health, June 1, 2009; 63(6): 433 - 438. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. Nyboe Andersen, V. Goossens, S. Bhattacharya, A.P. Ferraretti, M.S. Kupka, J. de Mouzon, K.G. Nygren, and The European IVF-monitoring (EIM) Consortium, for Assisted reproductive technology and intrauterine inseminations in Europe, 2005: results generated from European registers by ESHRE: ESHRE. The European IVF Monitoring Programme (EIM), for the European Society of Human Reproduction and Embryology (ESHRE) Hum. Reprod., June 1, 2009; 24(6): 1267 - 1287. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 The ESHRE Capri Workshop Group Intrauterine insemination Hum. Reprod. Update, May 1, 2009; 15(3): 265 - 277. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D. Hvidtjorn, L. Schieve, D. Schendel, B. Jacobsson, C. Svaerke, and P. Thorsen Cerebral Palsy, Autism Spectrum Disorders, and Developmental Delay in Children Born After Assisted Conception: A Systematic Review and Meta-analysis Arch Pediatr Adolesc Med, January 1, 2009; 163(1): 72 - 83. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. A. Horcajadas, P. Minguez, J. Dopazo, F. J. Esteban, F. Dominguez, L. C. Giudice, A. Pellicer, and C. Simon Controlled Ovarian Stimulation Induces a Functional Genomic Delay of the Endometrium with Potential Clinical Implications J. Clin. Endocrinol. Metab., November 1, 2008; 93(11): 4500 - 4510. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Nyboe Andersen, E. Carlsen, and A. Loft Trends in the use of intracytoplasmatic sperm injection marked variability between countries Hum. Reprod. Update, November 1, 2008; 14(6): 593 - 604. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Ziebe, P. Devroey, and on behalf of the State of the ART 2007 Workshop Gr Assisted reproductive technologies are an integrated part of national strategies addressing demographic and reproductive challenges Hum. Reprod. Update, November 1, 2008; 14(6): 583 - 592. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Hansen, L. Colvin, B. Petterson, J. J. Kurinczuk, N. de Klerk, and C. Bower Admission to hospital of singleton children born following assisted reproductive technology (ART) Hum. Reprod., June 1, 2008; 23(6): 1297 - 1305. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Nyboe Andersen, V. Goossens, A.P. Ferraretti, S. Bhattacharya, R. Felberbaum, J. de Mouzon, K.G. Nygren, and The European IVF-monitoring (EIM) Consortium, for Assisted reproductive technology in Europe, 2004: results generated from European registers by ESHRE Hum. Reprod., April 1, 2008; 23(4): 756 - 771. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Bowdin, C. Allen, G. Kirby, L. Brueton, M. Afnan, C. Barratt, J. Kirkman-Brown, R. Harrison, E. R Maher, and W. Reardon A survey of assisted reproductive technology births and imprinting disorders Hum. Reprod., December 1, 2007; 22(12): 3237 - 3240. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Hojgaard, L. D.M. Ottosen, U. Kesmodel, and H. J. Ingerslev Patient attitudes towards twin pregnancies and single embryo transfer a questionnaire study Hum. Reprod., October 1, 2007; 22(10): 2673 - 2678. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. Diedrich, B.C.J.M. Fauser, P. Devroey, G. Griesinger, and on behalf of the Evian Annual Reproduction (EVAR) The role of the endometrium and embryo in human implantation Hum. Reprod. Update, July 1, 2007; 13(4): 365 - 377. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. N. Andersen, V. Goossens, L. Gianaroli, R. Felberbaum, J. de Mouzon, and K.G. Nygren Assisted reproductive technology in Europe, 2003. Results generated from European registers by ESHRE Hum. Reprod., June 1, 2007; 22(6): 1513 - 1525. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Fedder, A. Gabrielsen, P. Humaidan, K. Erb, E. Ernst, and A. Loft Malformation rate and sex ratio in 412 children conceived with epididymal or testicular sperm Hum. Reprod., April 1, 2007; 22(4): 1080 - 1085. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A.A.A. Fiddelers, J.L. Severens, C.D. Dirksen, J.C.M. Dumoulin, J.A. Land, and J.L.H. Evers Economic evaluations of single- versus double-embryo transfer in IVF Hum. Reprod. Update, January 1, 2007; 13(1): 5 - 13. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Bungum, P. Humaidan, A. Axmon, M. Spano, L. Bungum, J. Erenpreiss, and A. Giwercman Sperm DNA integrity assessment in prediction of assisted reproduction technology outcome Hum. Reprod., January 1, 2007; 22(1): 174 - 179. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A.K. Ludwig, M. Glawatz, G. Griesinger, K. Diedrich, and M. Ludwig Perioperative and post-operative complications of transvaginal ultrasound-guided oocyte retrieval: prospective study of >1000 oocyte retrievals Hum. Reprod., December 1, 2006; 21(12): 3235 - 3240. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E.J. Margalioth, A. Ben-Chetrit, M. Gal, and T. Eldar-Geva Investigation and treatment of repeated implantation failure following IVF-ET Hum. Reprod., December 1, 2006; 21(12): 3036 - 3043. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G.H. Westerveld, C.M. Korver, A.M.M. van Pelt, N.J. Leschot, F. van der Veen, S. Repping, and M.P. Lombardi Mutations in the testis-specific NALP14 gene in men suffering from spermatogenic failure Hum. Reprod., December 1, 2006; 21(12): 3178 - 3184. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. van Wely, M. Twisk, B.W. Mol, and F. van der Veen Is twin pregnancy necessarily an adverse outcome of assisted reproductive technologies? Hum. Reprod., November 1, 2006; 21(11): 2736 - 2738. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. L. Zhu, O. Basso, C. Obel, C. Bille, and J. Olsen Infertility, infertility treatment, and congenital malformations: Danish national birth cohort BMJ, September 30, 2006; 333(7570): 679. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Salumets, A.-M. Suikkari, S. Makinen, H. Karro, A. Roos, and T. Tuuri Frozen embryo transfers: implications of clinical and embryological factors on the pregnancy outcome Hum. Reprod., September 1, 2006; 21(9): 2368 - 2374. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M.J. Pelinck, N.E.A. Vogel, A. Hoek, A.H.M. Simons, E.G.J.M. Arts, M.H. Mochtar, S. Beemsterboer, M.N. Hondelink, and M.J. Heineman Cumulative pregnancy rates after three cycles of minimal stimulation IVF and results according to subfertility diagnosis: a multicentre cohort study Hum. Reprod., September 1, 2006; 21(9): 2375 - 2383. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E.C. Haagen, R.P.M.G. Hermens, W.L.D.M. Nelen, D.D.M. Braat, R.P.T.M. Grol, and J.A.M. Kremer Subfertility guidelines in Europe: the quantity and quality of intrauterine insemination guidelines Hum. Reprod., August 1, 2006; 21(8): 2103 - 2109. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. A.A. Fiddelers, A. P.A. van Montfoort, C. D. Dirksen, J. C.M. Dumoulin, J. A. Land, G. A.J. Dunselman, J.M. Janssen, J. L. Severens, and J. L.H. Evers Single versus double embryo transfer: cost-effectiveness analysis alongside a randomized clinical trial Hum. Reprod., August 1, 2006; 21(8): 2090 - 2097. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
N. Gleicher, A. Weghofer, and D. Barad A formal comparison of the practice of assisted reproductive technologies between Europe and the USA Hum. Reprod., August 1, 2006; 21(8): 1945 - 1950. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D. Hvidtjorn, J. Grove, D. E. Schendel, M. Vaeth, E. Ernst, L. F. Nielsen, and P. Thorsen Cerebral Palsy Among Children Born After in Vitro Fertilization: The Role of Preterm Delivery--A Population-Based, Cohort Study Pediatrics, August 1, 2006; 118(2): 475 - 482. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
The European Ivf-monitoring programme (EIM) and for the European Society of Human Reproduction and Assisted reproductive technology in Europe, 2002. Results generated from European registers by ESHRE Hum. Reprod., July 1, 2006; 21(7): 1680 - 1697. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. De Neubourg and J. Gerris What about the remaining twins since single-embryo transfer? How far can (should) we go? Hum. Reprod., April 1, 2006; 21(4): 843 - 846. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 L. A. Schieve The promise of single-embryo transfer. N. Engl. J. Med., March 16, 2006; 354(11): 1190 - 1193. [Full Text] [PDF]
|
|
|
|
|
|
P.E. Levi Setti, E. Albani, P.V. Novara, A. Cesana, and G. Morreale Cryopreservation of supernumerary oocytes in IVF/ICSI cycles Hum. Reprod., February 1, 2006; 21(2): 370 - 375. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. Lampic, A. S. Svanberg, P. Karlstrom, and T. Tyden Fertility awareness, intentions concerning childbearing, and attitudes towards parenthood among female and male academics Hum. Reprod., February 1, 2006; 21(2): 558 - 564. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. Klemetti, T. Sevon, M. Gissler, and E. Hemminki Complications of IVF and ovulation induction Hum. Reprod., December 1, 2005; 20(12): 3293 - 3300. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Luconi, S. Torcia, D. Grillo, M. T. Fiorenza, G. Forti, F. Mangia, and E. Baldi Enhancement of mouse sperm motility by the PI3-kinase inhibitor LY294002 does not result in toxic effects on preimplantation embryo development Hum. Reprod., December 1, 2005; 20(12): 3500 - 3504. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. Schmidt, B.E. Holstein, U. Christensen, and J. Boivin Communication and coping as predictors of fertility problem stress: cohort study of 816 participants who did not achieve a delivery after 12 months of fertility treatment Hum. Reprod., November 1, 2005; 20(11): 3248 - 3256. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Z. Pandian, A. Templeton, G. Serour, and S. Bhattacharya Number of embryos for transfer after IVF and ICSI: a Cochrane review Hum. Reprod., October 1, 2005; 20(10): 2681 - 2687. [Abstract] [Full Text] [PDF]
|
|