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Hum. Reprod. Advance Access originally published online on May 12, 2005
Human Reproduction 2005 20(9):2628-2631; doi:10.1093/humrep/dei081
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© The Author 2005. Published by Oxford University Press on behalf of the European Society of Human Reproduction and Embryology. All rights reserved. For Permissions, please email: journals.permissions{at}oupjournals.org

Hysteroscopy may be justified after two miscarriages

A. Weiss1, E. Shalev1,2,3 and S. Romano1

1 Department of Obstetrics and Gynecology, Ha'Emek Medical Center, Afula, 18101 and 2 Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel

3 To whom correspondence should be addressed at: Department of Obstetrics and Gynecology, Ha'Emek Medical Center, Afula, 18101, Israel. Email: shaleve{at}tx.technion.ac.il

BACKGROUND: Recurrent pregnancy loss is traditionally investigated after three or more consecutive pregnancy losses. Although there is a trend to start investigation after two miscarriages, data are not available to date to justify this approach. We sought to compare the frequency of uterine anomalies between women referred to hysteroscopy for repeated miscarriages after two, and three or more, miscarriages respectively. METHODS: A retrospective analysis of acquired and congenital uterine anomalies in all patients undergoing hysteroscopy for repeated pregnancy loss at an academic and referral medical centre. RESULTS: Hysteroscopy was performed on 165 women referred for recurrent pregnancy loss: 67 after two and 98 after three or more consecutive miscarriages. The rate of uterine anomalies did not differ significantly and was 32 versus 28% respectively. CONCLUSIONS: Hysteroscopy may be justified following two spontaneous pregnancy losses.

Key words: hysteroscopy/recurrent miscarriage/uterine anomalies


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S. H. Saravelos, K. A. Cocksedge, and T.-C. Li
Prevalence and diagnosis of congenital uterine anomalies in women with reproductive failure: a critical appraisal
Hum. Reprod. Update, September 1, 2008; 14(5): 415 - 429.
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