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Hum. Reprod. Advance Access originally published online on June 22, 2006
Human Reproduction 2006 21(11):2736-2738; doi:10.1093/humrep/del249
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© The Author 2006. Published by Oxford University Press on behalf of the European Society of Human Reproduction and Embryology. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

OPINION

Is twin pregnancy necessarily an adverse outcome of assisted reproductive technologies?

M. van Wely1,3, M. Twisk1, B.W. Mol1,2 and F. van der Veen1

1 Center for Reproductive Medicine, Academic Medical Center, Amsterdam and 2 Department of Obstetrics and Gynaecology, Máxima Medical Center, Veldhoven, The Netherlands

3 To whom correspondence should be addressed at: Center for Reproductive Medicine, Academic Medical Center, Meibergdreef 9, H4-213, 1105 AZ Amsterdam, The Netherlands. E-mail: m.vanwely{at}amc.uva.nl

It has recently been suggested that the measure of success of assisted reproductive technologies (ART) should be the birth of a singleton baby, whereas a twin pregnancy should be considered as a complication. Although the maternal and neonatal complications in twin pregnancies are significantly higher than those in singleton pregnancies, the classification of a twin pregnancy as a complication of ART is in our opinion debatable. Most twin pregnancies result in the birth of two healthy babies, with little or no complication for the mother, and only few twin pregnancies results in serious morbidity of the mother and of one or both of the children. The crux of our arguments is that one should consider those cases as poor outcomes and not a twin pregnancy per se.

Key words: artificial reproductive technologies (ART)/complications/twin pregnancy


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