Hum. Reprod. Advance Access originally published online on March 21, 2007
Human Reproduction 2007 22(6):1506-1512; doi:10.1093/humrep/dem046
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
NEW DEBATE |
International estimates of infertility prevalence and treatment-seeking: potential need and demand for infertility medical care
1 School of Psychology, Cardiff University, Tower Building, Park Place, Wales CF10 3AT, UK 2 Department of Obstetrics and Gynecology, McMaster University, Hamilton and Department of Obstetrics and Gynaecology, Dalhousie University, Halifax, Canada 3 IVF-Clinic, Sophiahemmet Hospital, Stockholm, Sweden
4 Correspondence address. Tel: +12920876707; Fax: +12920874858; E-mail: boivin{at}cardiff.ac.uk
INTRODUCTION: The purpose of the present study was to review existing population surveys on the prevalence of infertility and proportion of couples seeking medical help for fertility problems.
METHODS: Population surveys, reporting the prevalence of infertility and proportion of couples seeking help in more and less developed countries, were reviewed.
RESULTS: Estimates on the prevalence of infertility came from 25 population surveys sampling 172 413 women. The 12-month prevalence rate ranged from 3.5% to 16.7% in more developed nations and from 6.9% to 9.3% in less-developed nations, with an estimated overall median prevalence of 9%. In 17 studies sampling 6410 women, the proportion of couples seeking medial care was, on average, 56.1% (range 42–76.3%) in more developed countries and 51.2% (range 27–74.1%) in less developed countries. The proportion of people actually receiving care was substantially less, 22.4%. Based on these estimates and on the current world population, 72.4 million women are currently infertile; of these, 40.5 million are currently seeking infertility medical care.
CONCLUSIONS: The current evidence indicates a 9% prevalence of infertility (of 12 months) with 56% of couples seeking medical care. These estimates are lower than those typically cited and are remarkably similar between more and less developed countries.
Key words: infertility/population/prevalence/treatment-seeking
Submitted on October 6, 2006; resubmitted on December 22, 2006; accepted on January 2, 2007.
![]()
CiteULike
Connotea
Del.icio.us What's this?
This article has been cited by other articles:
![]() |
M. Brandes, J.O.M. van der Steen, S.B. Bokdam, C.J.C.M. Hamilton, J.P. de Bruin, W.L.D.M. Nelen, and J.A.M. Kremer When and why do subfertile couples discontinue their fertility care? A longitudinal cohort study in a secondary care subfertility population Hum. Reprod., December 1, 2009; 24(12): 3127 - 3135. [Abstract] [Full Text] [PDF] |
||||
![]() |
S.L. Gudmundsdottir, W.D. Flanders, and L.B. Augestad Physical activity and fertility in women: the North-Trondelag Health Study Hum. Reprod., December 1, 2009; 24(12): 3196 - 3204. [Abstract] [Full Text] [PDF] |
||||
![]() |
M. Y. Makuch, C. A. Petta, M. J. D. Osis, and L. Bahamondes Low priority level for infertility services within the public health sector: a Brazilian case study Hum. Reprod., November 17, 2009; (2009) dep405v1. [Abstract] [Full Text] [PDF] |
||||
![]() |
K. Hammarberg, H.J.R. Rowe, and J.R.W. Fisher Early post-partum adjustment and admission to parenting services in Victoria, Australia after assisted conception Hum. Reprod., November 1, 2009; 24(11): 2801 - 2809. [Abstract] [Full Text] [PDF] |
||||
![]() |
I. W.H. van Empel, W. L.D.M. Nelen, E. T. Tepe, E. A.P. van Laarhoven, C. M. Verhaak, and J. A.M. Kremer Weaknesses, strengths and needs in fertility care according to patients Hum. Reprod., October 27, 2009; (2009) dep362v1. [Abstract] [Full Text] [PDF] |
||||
![]() |
M. A. Edson, A. K. Nagaraja, and M. M. Matzuk The Mammalian Ovary from Genesis to Revelation Endocr. Rev., October 1, 2009; 30(6): 624 - 712. [Abstract] [Full Text] [PDF] |
||||
![]() |
S.J. Dyer International estimates on infertility prevalence and treatment seeking: potential need and demand for medical care Hum. Reprod., September 1, 2009; 24(9): 2379 - 2380. [Full Text] [PDF] |
||||
![]() |
S. Wilkes, N. Hall, A. Crosland, A. Murdoch, and G. Rubin Patient experience of infertility management in primary care: an in-depth interview study Fam. Pract., August 1, 2009; 26(4): 309 - 316. [Abstract] [Full Text] [PDF] |
||||
![]() |
K. M. Lowther, V. N. Weitzman, D. Maier, and L. M. Mehlmann Maturation, Fertilization, and the Structure and Function of the Endoplasmic Reticulum in Cryopreserved Mouse Oocytes Biol Reprod, July 1, 2009; 81(1): 147 - 154. [Abstract] [Full Text] [PDF] |
||||
![]() |
K. Dieterich, R. Zouari, R. Harbuz, F. Vialard, D. Martinez, H. Bellayou, N. Prisant, A. Zoghmar, M. R. Guichaoua, I. Koscinski, et al. The Aurora Kinase C c.144delC mutation causes meiosis I arrest in men and is frequent in the North African population Hum. Mol. Genet., April 1, 2009; 18(7): 1301 - 1309. [Abstract] [Full Text] [PDF] |
||||
![]() |
J. Collins Mild stimulation for in vitro fertilization: making progress downward Hum. Reprod. Update, January 1, 2009; 15(1): 1 - 3. [Full Text] [PDF] |
||||
![]() |
W. Ombelet, I. Cooke, S. Dyer, G. Serour, and P. Devroey Infertility and the provision of infertility medical services in developing countries Hum. Reprod. Update, November 1, 2008; 14(6): 605 - 621. [Abstract] [Full Text] [PDF] |
||||
![]() |
P. Grasa, K. Coward, C. Young, and J. Parrington The pattern of localization of the putative oocyte activation factor, phospholipase C{zeta}, in uncapacitated, capacitated, and ionophore-treated human spermatozoa Hum. Reprod., November 1, 2008; 23(11): 2513 - 2522. [Abstract] [Full Text] [PDF] |
||||
![]() |
K. Nygren and F. Zegers-Hochschild Documentation of infertility prevalence, treatment access and treatment outcomes in developing countries ESHRE Monogr, July 1, 2008; 2008(1): 5 - 7. [Full Text] [PDF] |
||||
![]() |
K. Hammarberg, J.R.W. Fisher, and H.J. Rowe Women's experiences of childbirth and post-natal healthcare after assisted conception Hum. Reprod., July 1, 2008; 23(7): 1567 - 1573. [Abstract] [Full Text] [PDF] |
||||
![]() |
G.I. Serour Medical and socio-cultural aspects of infertility in the Middle East ESHRE Monogr, July 1, 2008; 2008(1): 34 - 41. [Abstract] [Full Text] [PDF] |
||||
![]() |
S.J. Dyer Infertility-related reproductive health knowledge and help-seeking behaviour in African countries ESHRE Monogr, July 1, 2008; 2008(1): 29 - 33. [Abstract] [Full Text] [PDF] |
||||
![]() |
J. Bellver, S. R. Soares, C. Alvarez, E. Munoz, A. Ramirez, C. Rubio, V. Serra, J. Remohi, and A. Pellicer The role of thrombophilia and thyroid autoimmunity in unexplained infertility, implantation failure and recurrent spontaneous abortion Hum. Reprod., February 1, 2008; 23(2): 278 - 284. [Abstract] [Full Text] [PDF] |
||||
![]() |
N. Soullier, J. Bouyer, J.L. Pouly, J. Guibert, and E. de La Rochebrochard Estimating the success of an in vitro fertilization programme using multiple imputation Hum. Reprod., January 1, 2008; 23(1): 187 - 192. [Abstract] [Full Text] [PDF] |
||||
![]() |
F. Feroze-Zaidi, L. Fusi, M. Takano, J. Higham, M. S. Salker, T. Goto, S. Edassery, K. Klingel, K. M. Boini, M. Palmada, et al. Role and Regulation of the Serum- and Glucocorticoid-Regulated Kinase 1 in Fertile and Infertile Human Endometrium Endocrinology, October 1, 2007; 148(10): 5020 - 5029. [Abstract] [Full Text] [PDF] |
||||
![]() |
A. H Balen and A. J Rutherford Management of infertility BMJ, September 22, 2007; 335(7620): 608 - 611. [Full Text] [PDF] |
||||








