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Hum. Reprod. Advance Access originally published online on June 12, 2007
Human Reproduction 2007 22(8):2302-2308; doi:10.1093/humrep/dem113
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© The Author 2007. Published by Oxford University Press on behalf of the European Society of Human Reproduction and Embryology. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

Attitudes towards human reproductive cloning, assisted reproduction and gene selection: a survey of 4600 British twins

B. Prainsack1,2,3,*, L.F. Cherkas2 and T.D. Spector2

1 Life Science Governance Research Platform, Department of Political Science, University of Vienna, Universitätsstraße 7, A-1010 Wien, Vienna, Austria 2 Twin Research and Genetic Epidemiology Unit, St Thomas' Hospital Campus, King's College, London, UK

3 Correspondence address. Tel: +43-650-9259723; E-mail: barbara.prainsack{at}univie.ac.at

BACKGROUND: Surveys have shown opposition to human reproductive cloning (HRC) in many countries. Views of identical (monozygotic, MZ) twins are of particular interest, as they naturally share 100% of their genes. We investigated attitudes of British twins towards HRC in the context of assisted reproduction technologies (ART) and gene selection.

METHODS: About 4651 identical and non-identical (dizygotic, DZ) twins expressed their degree of agreement or disagreement to nine statements relating to ART, gene selection and HRC in a self-completion questionnaire.

RESULTS: Most subjects (70% and 78% respectively) did not regard the use of medical technologies to treat infertility as interfering with either nature or God's will, despite believing that infertility is not a disease (54%). Attitudes to gene selection and HRC were context dependent, with more favourable views towards preventing serious diseases than towards enhancing traits. About 44% supported a permanent ban of HRC. MZ twins were significantly more likely to agree that HRC should be allowed for medical purposes, such as saving a sibling's life, than were DZ twins. Increasing religiosity generally correlated with more negative attitudes.

CONCLUSIONS: Many attitudes are context dependent. More positive views of MZ twins towards HRC could be linked to their experience with being genetically identical.

Key words: survey/attitudes/twins/assisted reproduction/human reproductive cloning


* Visiting Fellow at the ESRC Centre for Economic and Social Aspects of Genomics, Cardiff University, UK.

Submitted on January 29, 2007; resubmitted on March 29, 2007; accepted on April 2, 2007.


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E. Harcourt
Attitudes towards human reproductive cloning, ART and gene selection
Hum. Reprod., October 1, 2009; 24(10): 2674 - 2674.
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B. Prainsack
Reply: Attitudes towards human reproductive cloning, ART and gene selection
Hum. Reprod., October 1, 2009; 24(10): 2674 - 2674.
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