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Hum. Reprod. Advance Access originally published online on November 13, 2007
Human Reproduction 2008 23(1):85-90; doi:10.1093/humrep/dem361
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© The Author 2007. Published by Oxford University Press on behalf of the European Society of Human Reproduction and Embryology. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

Defining poor and optimum performance in an IVF programme

Jose A. Castilla1,7, Juana Hernandez2, Yolanda Cabello3, Alejandro Lafuente1, Nuria Pajuelo4, Javier Marqueta5, Buenaventura Coroleu (Assisted Reproductive Technology Register of the Spanish Fertility Society)6

1 Unidad de Reproducción, HU Virgen de las Nieves, E-18014 Granada, Spain 2 Servicio de Ginecologia y Obstetricia, Hospital San Millan, Logroño, Spain 3 FIV Recoletos, Madrid, Spain 4 Dynamic Solutions, Madrid, Spain 5 Instituto Balear de Infertilidad, Palma, Mallorca, Spain 6 Servicio de Medicina de la Reproducción, Departamento de Obstetricia, Ginecología y Reproducción, Institut Universitari Dexeus, Barcelona, Spain

7 Correspondence address. E-mail: josea.castilla.sspa{at}juntadeandalucia.es

BACKGROUND: At present there is considerable interest in healthcare administration, among professionals and among the general public concerning the quality of programmes of assisted reproduction. There exist various methods for comparing and analysing the results of clinical activity, with graphical methods being the most commonly used for this purpose. As yet, there is no general consensus as to how the poor performance (PP) or optimum performance (OP) of assisted reproductive technologies should be defined.

METHODS: Data from the IVF/ICSI register of the Spanish Fertility Society were used to compare and analyse different definitions of PP or OP. The primary variable best reflecting the quality of an IVF/ICSI programme was taken to be the percentage of singleton births per IVF/ICSI cycle initiated. Of the 75 infertility clinics that took part in the SEF-2003 survey, data on births were provided by 58. A total of 25 462 cycles were analysed. The following graphical classification methods were used: ranking of the proportion of singleton births per cycles started in each centre (league table), Shewhart control charts, funnel plots, best and worst-case scenarios and state of the art methods.

RESULTS: The clinics classified as producing PP or OP varied considerably depending on the classification method used. Only three were rated as providing ‘PP’ or ‘OP’ by all methods, unanimously. Another four clinics were classified as ‘poor’ or ‘optimum’ by all the methods except one.

CONCLUSIONS: On interpreting the results derived from IVF/ICSI centres, it is essential to take into account the characteristics of the method used for this purpose.

Key words: IVF/league table/outcome assessment/quality of care

Submitted on June 1, 2007; resubmitted on July 24, 2007; accepted on September 5, 2007.


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