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Hum. Reprod. Advance Access originally published online on July 18, 2008
Human Reproduction 2008 23(12):2629-2645; doi:10.1093/humrep/den238
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© The Author 2008. Published by Oxford University Press on behalf of the European Society of Human Reproduction and Embryology. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

ESHRE PGD Consortium data collection VIII: cycles from January to December 2005 with pregnancy follow-up to October 2006

V. Goossens1, G. Harton2, C. Moutou3, P.N. Scriven4, J. Traeger-Synodinos5, K. Sermon6 and J.C. Harper7,8

1 ESHRE Central Office, Meerstraat 60, 1852 Grimbergen, Belgium 2 Genetics and IVF Institute, 3015 Williams Drive, Fairfax, VA 22031, USA 3 Service de la Biologie de la Reproduction, SIHCUS-CMCO, 19, Rue Louis Pasteur, BP120, 67303 Schiltigheim, France 4 Cytogenetics Department and Centre for Preimplantation Genetic Diagnosis, Guy’s and St Thomas’ NHS Foundation Trust, Guy’s Hospital, Great Maze Pond, London SE1 9RT, UK 5 Laboratory of Medical Genetics, University of Athens, St Sophia’s Children’s Hospital, 11527 Athens, Greece 6 Department of Embryology and Genetics of the VUB and Centre for Medical Genetics of The Universitair Ziekenhuis Brussel, Laarbeeklaan 101, 1090 Brussels, Belgium 7 UCL Centre for PGD, Institute for Women’s Health, University College London, 86-96 Chenies Mews, WC1E6HX London, UK

8 Correspondence address. Tel: +44-20-7679-6072; E-mail: joyce.harper{at}ucl.ac.uk

The eighth report of the European Society of Human Reproduction and Embryology PGD Consortium is presented documenting cycles collected for the calendar year 2005 and follow-up of the pregnancies and babies born until October 2006 which resulted from these cycles. For the first time, the delivery rates for each indication are presented and also the pregnancy rates for each centre are reported anonymously. Since the first data collections, there has been a steady increase in the number of cycles, pregnancies and babies reported annually. For data collection VIII, 39 centres have participated, reporting on 3488 cycles to oocyte retrieval (OR), along with details of the follow-up on 845 pregnancies and 670 babies born. Five hundred and twenty OR were reported for chromosomal abnormalities, 108 OR for sexing for X-linked diseases, 500 OR for monogenic diseases, 2275 OR for preimplantation genetic screening and 85 OR for social sexing. Data VIII is compared with the cumulative data for data collections I–VII.

Key words: PGD/preimplantation genetic screening/fluorescence in situ hybridization/PCR/ESHRE PGD Consortium


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