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Human Reproduction, Vol. 3, No. 8, pp. 939-943, 1988
© 1988 European Society of Human Reproduction and Embryology

research-article

The treatment of infertility by the high intrauterine insemination of husband's washed spermatozoa

J.L. Yovich1,2 and P.L. Matson1

1PIVET Medical Centre 166–168 Cambridge Street, Perth, Western Australia 6007 2Department of Obstetrics and Gynaecology, University of Western Australia Nedlands, Western Australia 6009

A total of 345 couples with non-tubal infertility on an IVF waiting list underwent 702 treatment cydes involving daily intrauterine inseminatlons of husband's washed spermatozoa (AIH) over 3 days of the periovulatory period, following ovarian stimulation. Pregnancy rates achieved were depen dent upon the underlying Infertility disorder, with similar rates noted in those with a negative post-coltal test (15.8%) or where antispermatozoal antibodies were present in either the male (18.5%) or female (17.1%) partner. These rates were significantly higher than for couples with poor cervical mucus (4.7%), asthenozoospermia (0%), endonietriosis (mild, 7.7%; severe, 4.1%) or unexplained infertility (8.5%), while discrete oligozoospermia showed mid-range results (10.3%). Preg nancy outcome revealed a high level of early wastage (33.3%), mainly in the blighted ovum category, however congenital abnormalities (5.6%) were not significantly increased. It is concluded that the procedure of Affi should be considered for infertility due to poor sperm-mucus interaction, antispermatozoal antibodies and simple oligozoospermia, prior to IVF-related treatments.

Key words: artificial insemination (husband)/post-coital test/antispermatozoal antibodies/oligozoospermia


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