Human Reproduction, Vol. 4, No. 6, pp. 616-619, 1989
© 1989 European Society of Human Reproduction and Embryology
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Ultrasonic assessment of the endometrium as a predictor of oestrogen status in amenorrhoeic patients
1Central Hormonal Laboratories, Kupat Holim Hahistadrut Tel Aviv, Israel Department of Obstetrics and Gynaecology B, Meir Hospital, affiliated to Sackler Medical School, Tel Aviv University Kfar Saba, Tel Aviv, Israel
Thirty consecutive amenorhoeic patients were assessed with regard to the following: medical history, physical examination, pelvic ultrasonography, serum levels of 17-
oestradiol (E2), other relevant serum hormones and the response to a progesterone challenge test. The results showed a correlation coefficient of 71% (P = 0.001) between the E2 levels and the endometrial width and of 52% (P = 0.03) between the testosterone levels and the E2 levels. Linear regression of endometrial width against E2 levels showed
= 0.018 (R2 = 22%, P = 0.02). Patients with an endometrial width of 4 mm or less reported no bleeding or only scanty bleeding following progesterone and all the patients with an endometrial width of >5 mm responded to progesterone with normal menstrual bleeding
Key words: endometrium/MAP/ultrasonography