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Human Reproduction, Vol. 5, No. 8, pp. 955-958, 1990
© 1990 European Society of Human Reproduction and Embryology

other

Peritoneal fluid and infertility: a comparison of in-vitro fertilization of oocytes in peritoneal fluid and B2-Menezo medium

C. Wittemer1,, A. Menard2, and P. Dellenbach

Service de Gynécologie Obstétrique, Centro Médico-Chirurgical et Obstétrical 19, rue Louis Pasteur, BP120, 67303 Schiltigheim-cedex 2Service de Gynécologie Obstétrique, Hôpital Bichat 170, Boulevard Ney, 75018 Paris, France

Correspondence: 1To whom correspondence should be addressed

Peritoneal fluid probably has an important and complex role in fertility and infertility. In this study, in-vitro fertilization was attempted in peritoneal fluid and the classical B2-Menezo medium. Clinical criteria concerning male and female fertility and biological factors such as fresh semen quality, sperm survival, sperm-zona pellucida binding, cleavage and pregnancy rates were analysed for each infertile couple. The following results have been obtained. The quality of peritoneal fluid appears to fluctuate greatly from one woman to another. Routine use of peritoneal fluid as a culture medium during in-vitro fertilization should not be encouraged. Peritoneal fluid toxicity may explain some cases of ‘unexplained’ infertility.

Key words: infertility/in-vitro fertilization/peritoneal fluid


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