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Human Reproduction, Vol. 6, No. 5, pp. 613-618, 1991
© 1991 European Society of Human Reproduction and Embryology

editorial

The efficiency and efficacy of IVF and GIFT

Jean Cohen

Hôpital de Sèvres, 142 Grande Rue, 92310 Sèvres and 8, rue de Marignan 75008 Paris, France

Data relating to the rate of clinical pregnancy obtained with in-vitro fertilization - embryo transfer (IVF-ET) and gamete intra-Fallopian transfer (GIFT) are available for Australia, UK, USA and France. For IVF-ET the value is not affected by the indication but is affected by the age of the woman. The rate of spontaneous abortion, at ~ 20–25% also increases with age and is an important consideration in view of the increased age of patients undergoing IVF-ET. A take-home baby rate of 30% is obtained from an estimated 70% of clinical pregnancies leading to live births and an estimate of 42.8% pregnancies after three attempts. The greater number of oocytes transferred with GIFT may be associated with the increased frequency of multiple pregnancies.

Key words: assisted medical procreation/IVF-ET/frozen-thawed embryos/GIFT


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