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Human Reproduction, Vol. 6, No. 5, pp. 641-644, 1991
© 1991 European Society of Human Reproduction and Embryology

other

Effect of exogenous progesterone administration on the morphology of normally developing endometrium in the pre-implantation period

Tin-Chiu Li1,3, Peter Dockery2 and Ian D. Cooke

University of Sheffield, Jessop Hospital for Women Sheffield S3 7RE 1Department of Obstetrics and Gynaecology, University of Sheffield Sheffield, UK 2Department of Biomedical Science, University of Sheffield Sheffield, UK

Correspondence: 2To whom correspondence should be addressed

The effects on endometrial morphology of a single, intramuscular dose of 100 mg of progesterone administered in the early luteal phase, between days LH + 1 and LH + 6, were studied in a group (n = 8) of normal, fertile subjects by morphometric techniques and transmission electron microscopy. While the dose of progesterone administered consistently resulted in an increase of salivary progesterone concentration to above the upper limit of the reference range, no significant effect on endometrial development was observed; in particular, endometrial development was not advanced.

Key words: progesterone/endometrium/morphometry/transmission electron microscopy


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E. Tuckerman, S.M. Laird, R. Stewart, M. Wells, and T.C. Li
Markers of endometrial function in women with unexplained recurrent pregnancy loss: a comparison between morphologically normal and retarded endometrium
Hum. Reprod., January 1, 2004; 19(1): 196 - 205.
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